EE202100026A - Composition of compound comprising 3-hydroxycyclopentanone moiety and method of its stabilization - Google Patents

Composition of compound comprising 3-hydroxycyclopentanone moiety and method of its stabilization

Info

Publication number
EE202100026A
EE202100026A EEP202100026A EEP202100026A EE202100026A EE 202100026 A EE202100026 A EE 202100026A EE P202100026 A EEP202100026 A EE P202100026A EE P202100026 A EEP202100026 A EE P202100026A EE 202100026 A EE202100026 A EE 202100026A
Authority
EE
Estonia
Prior art keywords
composition
hydroxycyclopentanone
moiety
compound
stabilization
Prior art date
Application number
EEP202100026A
Other languages
Estonian (et)
Inventor
Ivar JÄRVING
Original Assignee
Aktsiaselts Kevelt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aktsiaselts Kevelt filed Critical Aktsiaselts Kevelt
Priority to EEP202100026A priority Critical patent/EE05864B1/en
Priority to PCT/IB2022/062615 priority patent/WO2023119188A1/en
Publication of EE202100026A publication Critical patent/EE202100026A/en
Publication of EE05864B1 publication Critical patent/EE05864B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to a composition comprising a compound having a 3-hydroxycyclopentanone moiety in its structure, an organic solvent comprising an alcohol or an ester or a mixture thereof, and a salt capable of dissociating in the solvent, or its constitutive ions. The invention further relates to a kit comprising such composition, to a method of preparing the composition, and to a method of stabilizing a compound having a 3-hydroxycyclopentanone moiety in the solvent using the salt.
EEP202100026A 2021-12-22 2021-12-22 Composition of compound comprising 3-hydroxycyclopentanone moiety and method of its stabilization EE05864B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EEP202100026A EE05864B1 (en) 2021-12-22 2021-12-22 Composition of compound comprising 3-hydroxycyclopentanone moiety and method of its stabilization
PCT/IB2022/062615 WO2023119188A1 (en) 2021-12-22 2022-12-21 Composition of compound comprising 3-hydroxycyclopentanone moiety and method of its stabilization

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EEP202100026A EE05864B1 (en) 2021-12-22 2021-12-22 Composition of compound comprising 3-hydroxycyclopentanone moiety and method of its stabilization

Publications (2)

Publication Number Publication Date
EE202100026A true EE202100026A (en) 2023-08-15
EE05864B1 EE05864B1 (en) 2024-02-15

Family

ID=86901468

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP202100026A EE05864B1 (en) 2021-12-22 2021-12-22 Composition of compound comprising 3-hydroxycyclopentanone moiety and method of its stabilization

Country Status (2)

Country Link
EE (1) EE05864B1 (en)
WO (1) WO2023119188A1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3851052A (en) * 1972-11-08 1974-11-26 Pfizer Stabilized e-series prostaglandins
US4301175A (en) * 1980-12-29 1981-11-17 The Upjohn Company E-Type prostaglandin compositions
WO2015113094A1 (en) * 2014-01-30 2015-08-06 Gebro Holding Gmbh Stable alcoholic solution of alprostadil
WO2017015690A1 (en) * 2015-07-27 2017-02-02 Gebro Holding Gmbh Concentrate containing alprostadil

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3954787A (en) * 1974-06-18 1976-05-04 Pfizer Inc. Stabilized E-series prostaglandins
US4070242A (en) * 1977-03-23 1978-01-24 Miles Laboratories, Inc. Method for the preparation of prostaglandin synthetase
US20050020646A1 (en) * 2003-06-25 2005-01-27 Pfizer Inc. Treatment of BPH
AT517555A1 (en) * 2015-07-27 2017-02-15 Gebro Holding Gmbh Concentrate containing alprostadil
RU2695068C1 (en) * 2018-06-26 2019-07-19 Общество с ограниченной ответственностью "Гурус БиоФарм" Agent for treating chronic obliterating peripheral vascular diseases based on prostaglandin
CN110193084A (en) * 2019-07-02 2019-09-03 付纪军 It is a kind of containing Polyvinylcaprolactame-polyvinyl acetate-polyethyleneglycol-graft copolymer pharmaceutical preparation and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3851052A (en) * 1972-11-08 1974-11-26 Pfizer Stabilized e-series prostaglandins
US4301175A (en) * 1980-12-29 1981-11-17 The Upjohn Company E-Type prostaglandin compositions
WO2015113094A1 (en) * 2014-01-30 2015-08-06 Gebro Holding Gmbh Stable alcoholic solution of alprostadil
WO2017015690A1 (en) * 2015-07-27 2017-02-02 Gebro Holding Gmbh Concentrate containing alprostadil

Also Published As

Publication number Publication date
EE05864B1 (en) 2024-02-15
WO2023119188A1 (en) 2023-06-29

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