EE200300507A - Use of HIV protease inhibitors to block cell migration and / or invasion, tissue infiltration, and edema - Google Patents
Use of HIV protease inhibitors to block cell migration and / or invasion, tissue infiltration, and edemaInfo
- Publication number
- EE200300507A EE200300507A EEP200300507A EEP200300507A EE200300507A EE 200300507 A EE200300507 A EE 200300507A EE P200300507 A EEP200300507 A EE P200300507A EE P200300507 A EEP200300507 A EE P200300507A EE 200300507 A EE200300507 A EE 200300507A
- Authority
- EE
- Estonia
- Prior art keywords
- edema
- invasion
- protease inhibitors
- cell migration
- hiv protease
- Prior art date
Links
- 206010030113 Oedema Diseases 0.000 title 1
- 230000004709 cell invasion Effects 0.000 title 1
- 230000012292 cell migration Effects 0.000 title 1
- 239000004030 hiv protease inhibitor Substances 0.000 title 1
- 230000008595 infiltration Effects 0.000 title 1
- 238000001764 infiltration Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2001RM000210A ITRM20010210A1 (en) | 2001-04-18 | 2001-04-18 | USE OF HUMAN IMMUNODEFICIENCY VIRUS PROTEASIS INHIBITORS (HIV) IN KAPOSI SARCOMA THERAPY, CANCER AND DISEASES THERAPY |
PCT/EP2002/004303 WO2002087583A2 (en) | 2001-04-18 | 2002-04-18 | Use of hiv-protease inhibitors to block cell migration and/or invasion, tissue infiltration and oedema formation |
Publications (1)
Publication Number | Publication Date |
---|---|
EE200300507A true EE200300507A (en) | 2004-02-16 |
Family
ID=11455472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EEP200300507A EE200300507A (en) | 2001-04-18 | 2002-04-18 | Use of HIV protease inhibitors to block cell migration and / or invasion, tissue infiltration, and edema |
Country Status (14)
Country | Link |
---|---|
US (1) | US20060088545A1 (en) |
EP (1) | EP1401447A2 (en) |
CN (1) | CN1700916A (en) |
AP (1) | AP2003002901A0 (en) |
BG (1) | BG108368A (en) |
CA (1) | CA2447748A1 (en) |
CZ (1) | CZ20033113A3 (en) |
EA (1) | EA006678B1 (en) |
EE (1) | EE200300507A (en) |
HU (1) | HUP0401199A2 (en) |
IT (1) | ITRM20010210A1 (en) |
MX (1) | MXPA03010380A (en) |
SK (1) | SK14212003A3 (en) |
WO (1) | WO2002087583A2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030138423A1 (en) * | 2001-12-14 | 2003-07-24 | Cedars-Sinai Medical Center | Method of treating inflammation with HIV-1 protease inhibitors and their derivatives |
US7812034B2 (en) * | 2003-11-04 | 2010-10-12 | City Of Hope | Method of using protease inhibitors for the treatment of liposarcomas |
US20090010990A1 (en) * | 2007-06-20 | 2009-01-08 | Little Marisa A | Process for depositing calcium phosphate therapeutic coatings with controlled release rates and a prosthesis coated via the process |
WO2011139378A1 (en) | 2010-05-06 | 2011-11-10 | The Feinstein Institute For Medical Research | Compounds and methods for treatment of systemic lupus erythematosus |
US20130317040A1 (en) * | 2010-12-22 | 2013-11-28 | The Feinstein Institute Of Medical Research | Methods for treating systemic lupus erythematosus using hiv protease inhibitors |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2779653B1 (en) * | 1998-06-11 | 2002-12-20 | Inst Nat Sante Rech Med | USE OF PROTEASOME MODULATING COMPOUNDS IN THERAPY |
WO2000033654A1 (en) * | 1998-12-04 | 2000-06-15 | University Of Maryland Biotechnology Institute | Use of protease inhibitors to modulate cellular pathways, immunity and therapies associated therewith |
-
2001
- 2001-04-18 IT IT2001RM000210A patent/ITRM20010210A1/en unknown
-
2002
- 2002-04-18 CZ CZ20033113A patent/CZ20033113A3/en unknown
- 2002-04-18 EA EA200301130A patent/EA006678B1/en not_active IP Right Cessation
- 2002-04-18 AP APAP/P/2003/002901A patent/AP2003002901A0/en unknown
- 2002-04-18 US US10/549,958 patent/US20060088545A1/en not_active Abandoned
- 2002-04-18 CN CNA028121260A patent/CN1700916A/en active Pending
- 2002-04-18 SK SK1421-2003A patent/SK14212003A3/en unknown
- 2002-04-18 HU HU0401199A patent/HUP0401199A2/en unknown
- 2002-04-18 CA CA002447748A patent/CA2447748A1/en not_active Abandoned
- 2002-04-18 EE EEP200300507A patent/EE200300507A/en unknown
- 2002-04-18 MX MXPA03010380A patent/MXPA03010380A/en not_active Application Discontinuation
- 2002-04-18 EP EP02766632A patent/EP1401447A2/en not_active Ceased
- 2002-04-18 WO PCT/EP2002/004303 patent/WO2002087583A2/en not_active Application Discontinuation
-
2003
- 2003-11-18 BG BG108368A patent/BG108368A/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP1401447A2 (en) | 2004-03-31 |
AP2003002901A0 (en) | 2003-12-31 |
ITRM20010210A1 (en) | 2002-10-18 |
US20060088545A1 (en) | 2006-04-27 |
MXPA03010380A (en) | 2004-03-16 |
CZ20033113A3 (en) | 2004-07-14 |
WO2002087583B1 (en) | 2003-11-20 |
CA2447748A1 (en) | 2002-11-07 |
HUP0401199A2 (en) | 2004-12-28 |
WO2002087583A3 (en) | 2002-12-19 |
EA200301130A1 (en) | 2004-04-29 |
EA006678B1 (en) | 2006-02-24 |
ITRM20010210A0 (en) | 2001-04-18 |
WO2002087583A2 (en) | 2002-11-07 |
CN1700916A (en) | 2005-11-23 |
BG108368A (en) | 2005-01-31 |
SK14212003A3 (en) | 2004-06-08 |
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EE200300507A (en) | Use of HIV protease inhibitors to block cell migration and / or invasion, tissue infiltration, and edema |