EE200300424A - Process for the preparation of phthalane - Google Patents

Process for the preparation of phthalane

Info

Publication number
EE200300424A
EE200300424A EEP200300424A EEP200300424A EE200300424A EE 200300424 A EE200300424 A EE 200300424A EE P200300424 A EEP200300424 A EE P200300424A EE P200300424 A EEP200300424 A EE P200300424A EE 200300424 A EE200300424 A EE 200300424A
Authority
EE
Estonia
Prior art keywords
sup
phthalane
preparation
halogen
sub
Prior art date
Application number
EEP200300424A
Other languages
Estonian (et)
Inventor
Khwaja Hamied Yusuf
Narayanrao Kankan Rajendra
Ramachandra Rao Dhanmaraj
Original Assignee
Cipla Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd. filed Critical Cipla Ltd.
Publication of EE200300424A publication Critical patent/EE200300424A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans

Abstract

Citalopram and other phthalanes are made by reacting a salt of a compound of formula (II) where R<SUP>1 </SUP>is halogen and R<SUP>2 </SUP>is halogen, trifluoromethyl, cyano or R-CO- where R is a C<SUB>1-4 </SUB>alkyl group, with cuprous cyanide.
EEP200300424A 2001-03-07 2002-03-07 Process for the preparation of phthalane EE200300424A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0105627.4A GB0105627D0 (en) 2001-03-07 2001-03-07 Preparation of phthalanes
PCT/GB2002/001054 WO2002070501A1 (en) 2001-03-07 2002-03-07 Preparation of phthalanes

Publications (1)

Publication Number Publication Date
EE200300424A true EE200300424A (en) 2003-12-15

Family

ID=9910160

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300424A EE200300424A (en) 2001-03-07 2002-03-07 Process for the preparation of phthalane

Country Status (19)

Country Link
US (1) US6903228B2 (en)
EP (1) EP1366034B1 (en)
AT (1) ATE368035T1 (en)
AU (1) AU2002236076B2 (en)
BG (1) BG108232A (en)
CA (1) CA2442613A1 (en)
CZ (1) CZ20032653A3 (en)
DE (1) DE60221360T2 (en)
EE (1) EE200300424A (en)
GB (1) GB0105627D0 (en)
HU (1) HUP0303467A2 (en)
LT (1) LT5167B (en)
LV (1) LV13132B (en)
PL (1) PL364834A1 (en)
RU (1) RU2276148C2 (en)
SK (1) SK12292003A3 (en)
TR (1) TR200301444T2 (en)
WO (1) WO2002070501A1 (en)
ZA (1) ZA200308039B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6967259B2 (en) * 2001-09-24 2005-11-22 Pharmachem Technologies Limited Process for the preparation of Citalopram intermediate
US7148364B2 (en) * 2002-01-07 2006-12-12 Sun Pharmaceutical Industries Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile
ES2194597B2 (en) * 2002-01-25 2004-08-01 Esteve Quimica, S.A. PROCEDURE FOR OBTAINING CITALOPRAM.
GB0206708D0 (en) * 2002-03-21 2002-05-01 Cipla Ltd Pharmaceutical salts
EP1486492A3 (en) * 2003-06-10 2005-02-23 Sun Pharmaceuticals Industries Ltd. A process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran.
KR101103118B1 (en) * 2007-11-02 2012-01-04 동아제약주식회사 Novel 1,3-dihydro-5-isobenzofurancarbonitrile derivatives and pharmaceutical composition for the treatment of premature ejaculation thereof
DE102010013069B4 (en) 2010-03-26 2012-12-06 Hommel-Etamic Gmbh measuring device

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
CA2291129C (en) * 1999-04-14 2002-10-22 H. Lundbeck A/S Method for the preparation of citalopram
ITMI991581A1 (en) * 1999-06-25 2001-01-15 Lundbeck & Co As H METHOD FOR THE PREPARATION OF CITALOPRAM
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
TR200201166T1 (en) * 2000-12-22 2002-10-21 H.Lundbecks A/S Method for the preparation of pure citalopram

Also Published As

Publication number Publication date
LT2003086A (en) 2004-07-26
HUP0303467A2 (en) 2004-01-28
CA2442613A1 (en) 2002-09-12
WO2002070501A1 (en) 2002-09-12
RU2003129659A (en) 2005-03-20
DE60221360D1 (en) 2007-09-06
US20040092755A1 (en) 2004-05-13
CZ20032653A3 (en) 2004-03-17
DE60221360T2 (en) 2007-11-29
LV13132B (en) 2004-06-20
RU2276148C2 (en) 2006-05-10
TR200301444T2 (en) 2004-09-21
EP1366034A1 (en) 2003-12-03
ZA200308039B (en) 2004-11-17
BG108232A (en) 2005-04-30
GB0105627D0 (en) 2001-04-25
EP1366034B1 (en) 2007-07-25
AU2002236076B2 (en) 2007-09-06
US6903228B2 (en) 2005-06-07
LT5167B (en) 2004-10-25
ATE368035T1 (en) 2007-08-15
PL364834A1 (en) 2004-12-27
SK12292003A3 (en) 2004-04-06

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