ECSP993222A - PROCESS FOR THE MANUFACTURE OF LIQUID FILLED CAPSULES - Google Patents

PROCESS FOR THE MANUFACTURE OF LIQUID FILLED CAPSULES

Info

Publication number
ECSP993222A
ECSP993222A ECSP993222A ECSP993222A EC SP993222 A ECSP993222 A EC SP993222A EC SP993222 A ECSP993222 A EC SP993222A EC SP993222 A ECSP993222 A EC SP993222A
Authority
EC
Ecuador
Prior art keywords
capsules
active agent
present
manufacture
dissolution rate
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Alex Rainer
Gerhards Jurgen
Kraemer Pittrof Ingeborg
Richard Oeschger
Thomas Rades
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP993222 priority Critical patent/ECSP993222A/en
Publication of ECSP993222A publication Critical patent/ECSP993222A/en

Links

Abstract

La presente invención se refiere a un procedimiento para el encapsulado de una masa de relleno sensible al cizallamiento en una cápsula, caracterizado porque dicha masa de relleno se calienta y seguidamente se enfria inmediatamente antes del encapsulado. La invención se refiere también a las cápsulas que pueden obtenerse mediante dicho procedimiento. El procedimiento de acuerdo con la presente invención npermite la obtención de cápsulas que presentan una alta y constante velocidad de disolución. La cantidad de agente activio ingerido puede por lo tanto disminuirse dado que el propio agente activo se disuelve rápidamente. Los costos totales del medicamento por lo tanto también disminuyen. La alta homogenidad (y por lo tanto la alta y constante velocidad de disolución) de las cápsulas elaboradas con el procedimiento de acuerdo con la presente invención garantiza una biodisponibilidad y efecto terapéutico reproducibles del agente activo que está contenido en la misma.The present invention relates to a process for encapsulating a shear-sensitive filler mass in a capsule, characterized in that said filler mass is heated and then cooled immediately prior to encapsulation. The invention also relates to the capsules that can be obtained by said procedure. The process according to the present invention does not allow the obtaining of capsules that have a high and constant dissolution rate. The amount of active agent ingested can therefore be decreased since the active agent itself dissolves rapidly. Total drug costs therefore also decrease. The high homogeneity (and therefore the high and constant dissolution rate) of the capsules made with the process according to the present invention guarantees a reproducible bioavailability and therapeutic effect of the active agent contained therein.

ECSP993222 1999-11-17 1999-11-17 PROCESS FOR THE MANUFACTURE OF LIQUID FILLED CAPSULES ECSP993222A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP993222 ECSP993222A (en) 1999-11-17 1999-11-17 PROCESS FOR THE MANUFACTURE OF LIQUID FILLED CAPSULES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP993222 ECSP993222A (en) 1999-11-17 1999-11-17 PROCESS FOR THE MANUFACTURE OF LIQUID FILLED CAPSULES

Publications (1)

Publication Number Publication Date
ECSP993222A true ECSP993222A (en) 2000-06-19

Family

ID=42044210

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP993222 ECSP993222A (en) 1999-11-17 1999-11-17 PROCESS FOR THE MANUFACTURE OF LIQUID FILLED CAPSULES

Country Status (1)

Country Link
EC (1) ECSP993222A (en)

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