Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filedfiledCritical
Priority to ECSP982743priorityCriticalpatent/ECSP982743A/en
Publication of ECSP982743ApublicationCriticalpatent/ECSP982743A/en
Low-Molecular Organic Synthesis Reactions Using Catalysts
(AREA)
Abstract
Un procedimiento para preparar pirrol-carboxamidas que se unen selectivamente a receptores GABA a ; que comprende hacer reaccionar 1,3 -cicloalcanodionas con bromoetilacetato, seguido por la reacción del producto resultante con un haluro de ácido, seguido por la reacción con una amina aromática y, finalmente, con una fuente de amonio a una temperatura elevada.A procedure for preparing pyrrole-carboxamides that selectively bind to GABA a receptors; which comprises reacting 1,3-cycloalkanediones with bromoethylacetate, followed by reaction of the resulting product with an acid halide, followed by reaction with an aromatic amine and, finally, with an ammonium source at an elevated temperature.