ECSP982672A - VITRONECTIN III RECEPTOR ANTAGONISTS - Google Patents

VITRONECTIN III RECEPTOR ANTAGONISTS

Info

Publication number
ECSP982672A
ECSP982672A ECSP982672A ECSP982672A EC SP982672 A ECSP982672 A EC SP982672A EC SP982672 A ECSP982672 A EC SP982672A EC SP982672 A ECSP982672 A EC SP982672A
Authority
EC
Ecuador
Prior art keywords
receptor antagonists
alkyl
vitronectin
iii receptor
halo
Prior art date
Application number
Other languages
Spanish (es)
Inventor
William Henry Miller
William E Bondinell
Dirk Heerding
James M Samanen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP982672 priority Critical patent/ECSP982672A/en
Publication of ECSP982672A publication Critical patent/ECSP982672A/en

Links

Abstract

Se describen compuestos de fórmula (I) que son antagonistas de receptores de vitronectina y son útiles en el tratamiento de osteoporosis: (gráfico), en la cual: A es Ch2 u o; R1 es H, halo o alquilo C1-6; R2 es H, alquilo C1-6 p Ch2NR¿¿R¿¿, X es 0 o CH2, Y es (gráfico), G es NR¿¿, SuO; R¿es H, alquilo C1-6, 0 alquilo C1-6, S-alquilo C1-6, Nr¿¿R¿¿ o halo; cada R¿¿es independientemente H alquilo C1-6; y o una sal farmacéuticamente aceptable de los mismos.Compounds of formula (I) are described which are vitronectin receptor antagonists and are useful in the treatment of osteoporosis: (graph), in which: A is Ch2 or o; R1 is H, halo or C1-6 alkyl; R2 is H, C1-6 alkyl p Ch2NR¿¿R¿¿, X is 0 or CH2, Y is (graph), G is NR¿¿, SuO; R¿ is H, C1-6 alkyl, 0 C1-6 alkyl, S-C1-6 alkyl, Nr¿¿R¿¿ or halo; each R¿¿is independently H C1-6alkyl; and or a pharmaceutically acceptable salt thereof.

ECSP982672 1998-09-18 1998-09-18 VITRONECTIN III RECEPTOR ANTAGONISTS ECSP982672A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP982672 ECSP982672A (en) 1998-09-18 1998-09-18 VITRONECTIN III RECEPTOR ANTAGONISTS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP982672 ECSP982672A (en) 1998-09-18 1998-09-18 VITRONECTIN III RECEPTOR ANTAGONISTS

Publications (1)

Publication Number Publication Date
ECSP982672A true ECSP982672A (en) 1999-04-13

Family

ID=42043591

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP982672 ECSP982672A (en) 1998-09-18 1998-09-18 VITRONECTIN III RECEPTOR ANTAGONISTS

Country Status (1)

Country Link
EC (1) ECSP982672A (en)

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