ECSP982468A - NICOTINAMIDE DERIVATIVES - Google Patents
NICOTINAMIDE DERIVATIVESInfo
- Publication number
- ECSP982468A ECSP982468A ECSP982468A ECSP982468A EC SP982468 A ECSP982468 A EC SP982468A EC SP982468 A ECSP982468 A EC SP982468A EC SP982468 A ECSP982468 A EC SP982468A
- Authority
- EC
- Ecuador
- Prior art keywords
- disease
- respiratory
- nicotinamide derivatives
- allergic
- inflammatory
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Esta invención se refiere a derivados de nicotinamida que son inhibidores selectivos de la fosfodiesterasa de tipo 4 (PDE4) y de la producción del factor de necrosis tumoral (TNF) y que, como tales, son útiles en el tratamiento de trastornos respiratorios, alérgicos, reumatoides, de regulación del peso corporal, inflamatorios y del sistema nervioso central, tales como asma, enfermedad obstructiva crónica pulmonar, síndrome de enfermedades respiratorias en adultos, shock, fibrosis, hipersensibilidad pulmonar, rinitis alérgica, dermatitis atópica, psoriasis, control de peso, artritis reumatoide, caquexia, enfermedad de Crohn, colitis ulcerosa, afecciones artriticas y otras enfermedades inflamatorias, depresión, demencia multi-infarto y SIDA.This invention relates to nicotinamide derivatives that are selective inhibitors of type 4 phosphodiesterase (PDE4) and of tumor necrosis factor (TNF) production and which, as such, are useful in the treatment of respiratory, allergic, rheumatoids, body weight regulation, inflammatory and central nervous system, such as asthma, chronic obstructive pulmonary disease, respiratory disease syndrome in adults, shock, fibrosis, pulmonary hypersensitivity, allergic rhinitis, atopic dermatitis, psoriasis, weight control, rheumatoid arthritis, cachexia, Crohn's disease, ulcerative colitis, arthritic conditions and other inflammatory diseases, depression, multi-infarct dementia and AIDS.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ECSP982468 ECSP982468A (en) | 1998-04-02 | 1998-04-02 | NICOTINAMIDE DERIVATIVES |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ECSP982468 ECSP982468A (en) | 1998-04-02 | 1998-04-02 | NICOTINAMIDE DERIVATIVES |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP982468A true ECSP982468A (en) | 1999-01-12 |
Family
ID=42043389
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ECSP982468 ECSP982468A (en) | 1998-04-02 | 1998-04-02 | NICOTINAMIDE DERIVATIVES |
Country Status (1)
Country | Link |
---|---|
EC (1) | ECSP982468A (en) |
-
1998
- 1998-04-02 EC ECSP982468 patent/ECSP982468A/en unknown
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