ECSP972350A - CYCLLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS UNDERSTANDING THEM, AND METHODS TO INHIBIT THE RELEASE OF THE β-AMYLOID PEPTIDE AND / OR ITS SYNTHESIS THROUGH THE USE OF SUCH COMPOUNDS - Google Patents
CYCLLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS UNDERSTANDING THEM, AND METHODS TO INHIBIT THE RELEASE OF THE β-AMYLOID PEPTIDE AND / OR ITS SYNTHESIS THROUGH THE USE OF SUCH COMPOUNDSInfo
- Publication number
- ECSP972350A ECSP972350A ECSP972350A ECSP972350A EC SP972350 A ECSP972350 A EC SP972350A EC SP972350 A ECSP972350 A EC SP972350A EC SP972350 A ECSP972350 A EC SP972350A
- Authority
- EC
- Ecuador
- Prior art keywords
- compounds
- synthesis
- release
- pharmaceutical compositions
- inhibit
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 230000015572 biosynthetic process Effects 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 238000003786 synthesis reaction Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- DZHSAHHDTRWUTF-SIQRNXPUSA-N amyloid-beta polypeptide 42 Chemical compound C([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(O)=O)[C@@H](C)CC)C(C)C)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(C)C)C1=CC=CC=C1 DZHSAHHDTRWUTF-SIQRNXPUSA-N 0.000 title 1
- 150000003951 lactams Chemical class 0.000 title 1
- 150000002596 lactones Chemical class 0.000 title 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
Landscapes
- Peptides Or Proteins (AREA)
Abstract
Se describen compuestos que inhiben la liberación de péptidos B-amiloides y/o su sintesis, y en consecuencia son útiles para tratar la enfermedad de Alzheimer. También se describen composiciones farmacéuticas que comprenden un compuesto que inhibe la liberación de péptidos B-amiloides y/o su sintesis como asi también métodos para tratar la enfermedad de Alzheimer profiláctica y terapéuticamente con tales composiciones farmacéuticas.Compounds that inhibit the release of B-amyloid peptides and / or their synthesis are described, and accordingly are useful in treating Alzheimer's disease. Pharmaceutical compositions comprising a compound that inhibits the release of B-amyloid peptides and / or their synthesis are also described as well as methods of treating Alzheimer's disease prophylactically and therapeutically with such pharmaceutical compositions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP972350 ECSP972350A (en) | 1997-12-23 | 1997-12-23 | CYCLLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS UNDERSTANDING THEM, AND METHODS TO INHIBIT THE RELEASE OF THE β-AMYLOID PEPTIDE AND / OR ITS SYNTHESIS THROUGH THE USE OF SUCH COMPOUNDS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP972350 ECSP972350A (en) | 1997-12-23 | 1997-12-23 | CYCLLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS UNDERSTANDING THEM, AND METHODS TO INHIBIT THE RELEASE OF THE β-AMYLOID PEPTIDE AND / OR ITS SYNTHESIS THROUGH THE USE OF SUCH COMPOUNDS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP972350A true ECSP972350A (en) | 1999-08-12 |
Family
ID=42043179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP972350 ECSP972350A (en) | 1997-12-23 | 1997-12-23 | CYCLLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS UNDERSTANDING THEM, AND METHODS TO INHIBIT THE RELEASE OF THE β-AMYLOID PEPTIDE AND / OR ITS SYNTHESIS THROUGH THE USE OF SUCH COMPOUNDS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP972350A (en) |
-
1997
- 1997-12-23 EC ECSP972350 patent/ECSP972350A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9714517A (en) | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising them and processes to inhibit beta-amyloid peptide release and / or its synthesis by using such compounds | |
| EA199900778A1 (en) | HETEROCYCLIC COMPOUNDS AND THEIR USE TO INHIBIT β-AMYLOID PEPTIDE | |
| AR016751A1 (en) | METHOD FOR INHIBITING THE RELEASE OF THE BETA-AMYLOID PEPTIDE IN A CELL, PHARMACEUTICAL COMPOSITION AND USEFUL COMPOUNDS IN THIS METHOD | |
| MX9709278A (en) | DIPEPTIDES THAT PROMOTE THE RELEASE OF GROWTH HORMONE, COMPOSITIONS THAT CONTAIN THEM AND USE THEM. | |
| PE20020802A1 (en) | LACTAM COMPOUND AS INHIBITOR OF THE RELEASE OF THE ß-AMYLOID PEPTIDE | |
| PA8503301A1 (en) | COMPOUNDS FOR THE TREATMENT OF THE ISCHEMIA | |
| GT199700079A (en) | TRICYCLES DERIVATIVES REPLACED WITH PHENYLAMINE | |
| CO4790174A1 (en) | ANALOGS OF PEPTIDE LH-RH, ITS USES AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM | |
| ES2091906T3 (en) | COMPOSITIONS INCLUDING DERIVATIVES OF AN OMEGA-CONOTOXIN PEPTIDE AND ITS USE IN THE TREATMENT OF NEURONAL DAMAGE RELATED TO ISCHEMIA. | |
| AR062931A2 (en) | COMPOUNDS THAT LINK TO AND ACTIVATE A THROMBOPOYETIN RECEPTOR, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE FOR THE PREPARATION OF MEDICINES | |
| MX9403386A (en) | PIRROLIDIN-3-IL-ALQUILPIPERIDINAS SUBSTITUTED. | |
| MX9301129A (en) | NEW CYCLOSPORINS AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM. | |
| BR9713404A (en) | esters of n- (aryl / heteroarylacetyl) amino acids, pharmaceutical compositions comprising them, and methods for inhibiting the release of beta-amyloid peptide and / or its synthesis by using such compounds. | |
| GT199900070A (en) | DERIVATIVES OF ISOTIAZOLE, USEFUL AS ANTI-CANCER AGENTS. | |
| GT199700089A (en) | DERIVATIVES 6.6 OR 6.7-SUBSTITUTED BICYCLES CONTAINING PIRIDO OR PIRIMIDO. | |
| SV1998000029A (en) | PIRAZINE COMPOUNDS REF. PG3186 | |
| MX9400255A (en) | ANALOGS OF OPIOID PEPTIDES, METHOD FOR PREPARATION AND PHARMACEUTICAL COMPOSITIONS INCLUDING THEM. | |
| MX9201730A (en) | NEW SUBSTITUTED FENILAZACICLOALCANOS ACTING CENTRALLY. | |
| ECSP941122A (en) | DERIVATIVES OF 5-ARYLINDOLS | |
| BG99177A (en) | NEW 7 BETA-SUBSTITUTED-4-AZA-5 ALPHA-CHOLESTANONE AS 5 ALPHA REDUCTASE INHIBITORS | |
| MX9301197A (en) | DERIVATIVES OF INDOL. | |
| CO5050328A1 (en) | SOLVENT SYSTEM FOR THE BEST PENETRATION OF PHARMACEUTICAL COMPOUNDS | |
| MX9304424A (en) | BENZIMIDAZOLES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCEDURE FOR THEIR PREPARATION. | |
| ES2148458T3 (en) | DERIVATIVES OF FENIL-4-THIAZOLES SUBSTITUTED, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM. | |
| MX9204613A (en) | ORGANIC NITRATES, PROCEDURES FOR ITS PREPARATION AND USE IN THE TREATMENT OF CARDIOVASCULAR DISEASES |