ECSP972201A - FUSION POLYPEPTIDES - Google Patents
FUSION POLYPEPTIDESInfo
- Publication number
- ECSP972201A ECSP972201A ECSP972201A ECSP972201A EC SP972201 A ECSP972201 A EC SP972201A EC SP972201 A ECSP972201 A EC SP972201A EC SP972201 A ECSP972201 A EC SP972201A
- Authority
- EC
- Ecuador
- Prior art keywords
- fusion polypeptides
- preparation
- intermediates
- fused
- polypeptides
- Prior art date
Links
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Los polipéptidos de fusión y sales del mismo que comprenden al menos un dominio de unión de IgE fusionado al menos un componente de seroalbúmina humana, opcionalmente vía un enlazante peptídico, y en particular polipéptidos de fusión diméricos que comprenden proteína HSA fusionada, en cada uno de sus amino y carboxi terminales, a un dominio extracelular de la cadena alfa del receptor de alta afinidad humano para la IgE (FeERIalfa); los procesos para la preparación de los mismos, los polipéptidos funcionalmente equivalentes que son intermediarios en su preparación, y los intermedios polipéptidos y oligonucleotidicos y vectores de los mismos. Ellos están indicados para usarse en la prevención y/o tratamiento de enfermedades alérgicas medianas por la IgR y padecimientos relacionados tales como la dermatitis atópica, asma atópica y curticaria crónica.Fusion polypeptides and salts thereof comprising at least one IgE binding domain fused to at least one component of human serum albumin, optionally via a peptide linker, and in particular dimeric fusion polypeptides comprising fused HSA protein, in each of its amino and carboxy termini, to an extracellular domain of the human IgE high affinity receptor alpha chain (FeERIalfa); the processes for the preparation thereof, the functionally equivalent polypeptides that are intermediates in their preparation, and the polypeptide and oligonucleotide intermediates and vectors thereof. They are indicated for use in the prevention and / or treatment of medium allergic IgR diseases and related conditions such as atopic dermatitis, atopic asthma and chronic curticaria.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ECSP972201 ECSP972201A (en) | 1997-07-25 | 1997-07-25 | FUSION POLYPEPTIDES |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ECSP972201 ECSP972201A (en) | 1997-07-25 | 1997-07-25 | FUSION POLYPEPTIDES |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP972201A true ECSP972201A (en) | 1999-01-19 |
Family
ID=42043032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ECSP972201 ECSP972201A (en) | 1997-07-25 | 1997-07-25 | FUSION POLYPEPTIDES |
Country Status (1)
Country | Link |
---|---|
EC (1) | ECSP972201A (en) |
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1997
- 1997-07-25 EC ECSP972201 patent/ECSP972201A/en unknown
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