ECSP972051A - TRIARYL COMPOUND - Google Patents

TRIARYL COMPOUND

Info

Publication number
ECSP972051A
ECSP972051A ECSP972051A ECSP972051A EC SP972051 A ECSP972051 A EC SP972051A EC SP972051 A ECSP972051 A EC SP972051A EC SP972051 A ECSP972051 A EC SP972051A
Authority
EC
Ecuador
Prior art keywords
compounds
biphenyl
fibenyl
arylcabonyloxy
azaryl
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Paul William Manley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP972051 priority Critical patent/ECSP972051A/en
Publication of ECSP972051A publication Critical patent/ECSP972051A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Compuestos de (4-oxi-3-(aril)fenil)-azarilo o -arilcaboniloxi, en la forma libre o de sal de adición de ácido, son útiles como productos farmacéuticos para el tratamiento y profilaxis de la inflamación; particularmente enfermedades inflamatorias u obstructivas de las vías respiratorias, por ejemplo, para terapia del asma. Los compuestos preferidos son nuevos compuestos de bifenil piridinas, bifenil benzamidas y fibenil fenilcarboxi. Los compuestos son inhibidores selectivos de la actividad de isoenzima PDE4 y también actúan para regular en descenso o inhibir la liberación de TNF-a(4-Oxy-3- (aryl) phenyl) -azaryl or -arylcabonyloxy compounds, in the free or acid addition salt form, are useful as pharmaceuticals for the treatment and prophylaxis of inflammation; particularly inflammatory or obstructive airway diseases, for example, for asthma therapy. Preferred compounds are new compounds of biphenyl pyridines, biphenyl benzamides and fibenyl phenylcarboxy. The compounds are selective inhibitors of PDE4 isoenzyme activity and also act to down-regulate or inhibit TNF-a release.

ECSP972051 1997-03-07 1997-03-07 TRIARYL COMPOUND ECSP972051A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP972051 ECSP972051A (en) 1997-03-07 1997-03-07 TRIARYL COMPOUND

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP972051 ECSP972051A (en) 1997-03-07 1997-03-07 TRIARYL COMPOUND

Publications (1)

Publication Number Publication Date
ECSP972051A true ECSP972051A (en) 1998-02-13

Family

ID=42042884

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP972051 ECSP972051A (en) 1997-03-07 1997-03-07 TRIARYL COMPOUND

Country Status (1)

Country Link
EC (1) ECSP972051A (en)

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