ECSP941064A - PREPARATION OF RANITIDINE CHLORHYDRATE FORM 1 - Google Patents

PREPARATION OF RANITIDINE CHLORHYDRATE FORM 1

Info

Publication number
ECSP941064A
ECSP941064A ECSP941064A ECSP941064A EC SP941064 A ECSP941064 A EC SP941064A EC SP941064 A ECSP941064 A EC SP941064A EC SP941064 A ECSP941064 A EC SP941064A
Authority
EC
Ecuador
Prior art keywords
ranitidine
ranitidine hydrochloride
preparation
solution
carbon atoms
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Teng-Ko Ngooi
Jeffrey David Mcgolrick
Casimir Antczak
James Lorne Anthony Tindall
Original Assignee
Torcan Chemical Ltda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torcan Chemical Ltda filed Critical Torcan Chemical Ltda
Publication of ECSP941064A publication Critical patent/ECSP941064A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Un procedimiento para preparar clorhidrato de ranitidina Forma 1, caracterizado porque comprende: formar una solución de clorhidrato de ranitidina en un solvente mixto, que comprende por lo menos un alcanol de 1 a 4 átomos de carbono y un hidrocarburo aromático de 6 a 10 átomos de carbono, siendo la relación en volumen de uno o varios alcanoles al hidrocarburo, de aproximadamente 1:1 a 1:2; e iniciar la cristalización del clorhidrato de ranitidina Forma 1 de dicha solución, en presencia de cristales de siembra de clorhidrato de ranitidina puro, Forma I.A process for preparing ranitidine hydrochloride Form 1, characterized in that it comprises: forming a solution of ranitidine hydrochloride in a mixed solvent, comprising at least one alkanol of 1 to 4 carbon atoms and an aromatic hydrocarbon of 6 to 10 carbon atoms. carbon, the volume ratio of one or more alkanols to the hydrocarbon being approximately 1: 1 to 1: 2; and starting the crystallization of ranitidine hydrochloride Form 1 of said solution, in the presence of seed crystals of pure ranitidine hydrochloride, Form I.

ECSP941064 1993-07-07 1994-04-04 PREPARATION OF RANITIDINE CHLORHYDRATE FORM 1 ECSP941064A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IE930508A IE72966B1 (en) 1993-07-07 1993-07-07 Preparation of form 1 ranitidine hydrochloride

Publications (1)

Publication Number Publication Date
ECSP941064A true ECSP941064A (en) 1994-11-16

Family

ID=11040008

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP941064 ECSP941064A (en) 1993-07-07 1994-04-04 PREPARATION OF RANITIDINE CHLORHYDRATE FORM 1

Country Status (2)

Country Link
EC (1) ECSP941064A (en)
IE (1) IE72966B1 (en)

Also Published As

Publication number Publication date
IE72966B1 (en) 1997-05-07
IE930508A1 (en) 1995-01-11

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