ECSP20016283A - METHODS TO TREAT AND / OR PREVENT GRAFT DISEASE IN FRONT OF THE HOST AND / OR ALVEOLAR HEMORRHAGE AND / OR VENO-OCLUSIVE DISEASE ASSOCIATED WITH TRANSPLANTATION OF HEMATOPOIETIC STEM CELLS - Google Patents
METHODS TO TREAT AND / OR PREVENT GRAFT DISEASE IN FRONT OF THE HOST AND / OR ALVEOLAR HEMORRHAGE AND / OR VENO-OCLUSIVE DISEASE ASSOCIATED WITH TRANSPLANTATION OF HEMATOPOIETIC STEM CELLSInfo
- Publication number
- ECSP20016283A ECSP20016283A ECSENADI202016283A ECDI202016283A ECSP20016283A EC SP20016283 A ECSP20016283 A EC SP20016283A EC SENADI202016283 A ECSENADI202016283 A EC SENADI202016283A EC DI202016283 A ECDI202016283 A EC DI202016283A EC SP20016283 A ECSP20016283 A EC SP20016283A
- Authority
- EC
- Ecuador
- Prior art keywords
- disease
- veno
- stem cells
- hematopoietic stem
- methods
- Prior art date
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
En un aspecto, la invención proporciona métodos para inhibir los efectos de la activación del complemento dependiente de MASP-2 en un sujeto humano que padece enfermedad de injerto contra hospedador y/o hemorragia alveolar difusa y/o enfermedad veno-oclusiva asociada a un trasplante de células madre hematopoyéticas. Los métodos comprenden la etapa de administrar, a un sujeto que lo necesite, una cantidad de un agente inhibidor de MASP-2 eficaz para inhibir la activación del complemento dependiente de MASP-2.In one aspect, the invention provides methods for inhibiting the effects of MASP-2-dependent complement activation in a human subject suffering from graft-versus-host disease and / or diffuse alveolar hemorrhage and / or transplant-associated veno-occlusive disease. of hematopoietic stem cells. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762545864P | 2017-08-15 | 2017-08-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP20016283A true ECSP20016283A (en) | 2020-04-22 |
Family
ID=71783773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ECSENADI202016283A ECSP20016283A (en) | 2017-08-15 | 2020-03-05 | METHODS TO TREAT AND / OR PREVENT GRAFT DISEASE IN FRONT OF THE HOST AND / OR ALVEOLAR HEMORRHAGE AND / OR VENO-OCLUSIVE DISEASE ASSOCIATED WITH TRANSPLANTATION OF HEMATOPOIETIC STEM CELLS |
Country Status (1)
Country | Link |
---|---|
EC (1) | ECSP20016283A (en) |
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2020
- 2020-03-05 EC ECSENADI202016283A patent/ECSP20016283A/en unknown
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