ECSP10010706A - ISOQUINOLINAS AND ISOQUINOLINONAS 6-REPLACED - Google Patents
ISOQUINOLINAS AND ISOQUINOLINONAS 6-REPLACEDInfo
- Publication number
- ECSP10010706A ECSP10010706A ECSP10010706A ECSP10010706A EC SP10010706 A ECSP10010706 A EC SP10010706A EC SP10010706 A ECSP10010706 A EC SP10010706A EC SP10010706 A ECSP10010706 A EC SP10010706A
- Authority
- EC
- Ecuador
- Prior art keywords
- isoquinolinonas
- isoquinolinas
- replaced
- rho kinase
- prevention
- Prior art date
Links
- 102000000568 rho-Associated Kinases Human genes 0.000 abstract 2
- 108010041788 rho-Associated Kinases Proteins 0.000 abstract 2
- -1 6-substituted isoquinoline Chemical class 0.000 abstract 1
- 102000011131 Myosin-Light-Chain Phosphatase Human genes 0.000 abstract 1
- 108010037801 Myosin-Light-Chain Phosphatase Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000006806 disease prevention Effects 0.000 abstract 1
- VDBNYAPERZTOOF-UHFFFAOYSA-N isoquinolin-1(2H)-one Chemical class C1=CC=C2C(=O)NC=CC2=C1 VDBNYAPERZTOOF-UHFFFAOYSA-N 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000026731 phosphorylation Effects 0.000 abstract 1
- 238000006366 phosphorylation reaction Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La invención se refiere a derivados de isoquinolina e isoquinolinona 6-sustituidos de la fórmula (I)(I)útiles para el tratamiento y/o la prevención de enfermedades asociadas con la cinasa Rho y/o la fosforilación mediada por la cinasa Rho de la fosfatasa de miosina de cadena ligera , y a composiciones que contienen dichos compuestos.The invention relates to 6-substituted isoquinoline and isoquinolinone derivatives of the formula (I) (I) useful for the treatment and / or prevention of diseases associated with Rho kinase and / or Rho kinase mediated phosphorylation of the light chain myosin phosphatase, and compositions containing said compounds.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08029605 | 2008-06-24 | ||
| US15314509P | 2009-02-17 | 2009-02-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP10010706A true ECSP10010706A (en) | 2011-01-31 |
Family
ID=44279991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP10010706 ECSP10010706A (en) | 2008-06-24 | 2010-12-22 | ISOQUINOLINAS AND ISOQUINOLINONAS 6-REPLACED |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP10010706A (en) |
-
2010
- 2010-12-22 EC ECSP10010706 patent/ECSP10010706A/en unknown
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