ECSP034781A - N- (2-ARILETIL) BENCILAMINS AS ANTAGONISTS OF THE 5-HT6 RECEIVER - Google Patents
N- (2-ARILETIL) BENCILAMINS AS ANTAGONISTS OF THE 5-HT6 RECEIVERInfo
- Publication number
- ECSP034781A ECSP034781A ECSP034781A ECSP034781A EC SP034781 A ECSP034781 A EC SP034781A EC SP034781 A ECSP034781 A EC SP034781A EC SP034781 A ECSP034781 A EC SP034781A
- Authority
- EC
- Ecuador
- Prior art keywords
- group
- optionally substituted
- alkyl
- hydrogen
- aromatic heterocycle
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Un compuesto de fórmula (Grafico) en el que X se selecciona del grupo constituido por -O-, -NH-, -S-, -SO2-, -CH2-, -CH(F)-, CH(OH)-,Y-C(O)-;R1 se selecciona del grupo constituido por fenilo opcionalmente sustituido, heterociclo aromático monociclito de 5 a 6 miembros opccionalmente sustituido que tiene un heteroátomo seleccionado del grupo constituido por nitrógeno, oxigeno y azufre y dicho heterociclo aromático monociclico de 5 a 6 miembros está opcionalmente benzocondensado; R2 se selecciona del grupo constituido por hidrogeno y alquilo C1-C3; R3 se selecciona del grupo constituido por hidrogeno, fluoro, y metilo; R4 se selecciona del grupo constituido por hidrógeno, alilo, alquilo C2- C4, alquilo C2-C4 fluorado, fenilo opcionalmente sustituido, fenilsulfonilo opcionalmente sustituido, bencilo opcionalmente sustituido, y heterociclo aromático monociclico de 5 a 6 miembros opcionalmente sustituido que tiene uno o dos heteroátomos seleccionados del grupo constituido por nitrógeno, oxigeno, y azúfre, con la condición de que R4 no sea fenilsulfonilo opcionalmente sustituido cuando X es -S02-; -CH2-, -CH(F)-, -CH(OH)-, 0- C(0)-; y sales farmacéuticamente aceptables del mismo.A compound of formula (Graph) in which X is selected from the group consisting of -O-, -NH-, -S-, -SO2-, -CH2-, -CH (F) -, CH (OH) -, YC (O) -; R1 is selected from the group consisting of optionally substituted phenyl, optionally substituted 5 to 6 membered monocyclic aromatic heterocycle having a heteroatom selected from the group consisting of nitrogen, oxygen and sulfur and said 5 to 6 monocyclic aromatic heterocycle members is optionally benzocondensed; R2 is selected from the group consisting of hydrogen and C1-C3 alkyl; R3 is selected from the group consisting of hydrogen, fluoro, and methyl; R4 is selected from the group consisting of hydrogen, allyl, C2-C4 alkyl, fluorinated C2-C4 alkyl, optionally substituted phenyl, optionally substituted phenylsulfonyl, optionally substituted benzyl, and optionally substituted 5 to 6 membered monocyclic aromatic heterocycle having one or two heteroatoms selected from the group consisting of nitrogen, oxygen, and sulfur, with the proviso that R4 is not optionally substituted phenylsulfonyl when X is -S02-; -CH2-, -CH (F) -, -CH (OH) -, 0- C (0) -; and pharmaceutically acceptable salts thereof.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27992801P | 2001-03-29 | 2001-03-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP034781A true ECSP034781A (en) | 2003-12-01 |
Family
ID=34589870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP034781 ECSP034781A (en) | 2001-03-29 | 2003-09-26 | N- (2-ARILETIL) BENCILAMINS AS ANTAGONISTS OF THE 5-HT6 RECEIVER |
Country Status (2)
| Country | Link |
|---|---|
| EC (1) | ECSP034781A (en) |
| UA (1) | UA76451C2 (en) |
-
2002
- 2002-03-15 UA UA2003098796A patent/UA76451C2/en unknown
-
2003
- 2003-09-26 EC ECSP034781 patent/ECSP034781A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| UA76451C2 (en) | 2006-08-15 |
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