ECSP034751A - DERIVATIVES OF PIPERIDINE ACILATED AS AGONISTS OF THE RECEIVER MELANOCORTINA-4 - Google Patents

DERIVATIVES OF PIPERIDINE ACILATED AS AGONISTS OF THE RECEIVER MELANOCORTINA-4

Info

Publication number
ECSP034751A
ECSP034751A ECSP034751A ECSP034751A EC SP034751 A ECSP034751 A EC SP034751A EC SP034751 A ECSP034751 A EC SP034751A EC SP034751 A ECSP034751 A EC SP034751A
Authority
EC
Ecuador
Prior art keywords
piperidine
derivatives
agonists
melanocortina
acilated
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Feroze Ujjainwalla
Mark Goulet
Lin Chu
Matthew J Wyvratt
Bonnie Louridas
Daniel Warner
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ECSP034751A publication Critical patent/ECSP034751A/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a piperidinas N-asiladas 4 sustituidas novedosas de fórmula estructural I: Estos derivados de piperidina asilada son efectivos como agonistas del receptor de melanocortina y son particularmente efectivos como agonistas selectivos del receptor de melanocortina-4 (MC-4R):Son por lo tanto útiles para el tratamiento y/o prevención de trastornos que responden a la activación de MC-$R, tales como obesidad, diabetes así como disfunción sexual masculina y femenina, en particular la disfunción eréctil masculina.The present invention relates to novel substituted N-asylated piperidines 4 of structural formula I: These derivatives of asylated piperidine are effective as melanocortin receptor agonists and are particularly effective as selective melanocortin-4 receptor agonists (MC-4R): They are therefore useful for the treatment and / or prevention of disorders that respond to the activation of MC-R, such as obesity, diabetes as well as male and female sexual dysfunction, in particular male erectile dysfunction.

ECSP034751 2001-02-28 2003-08-27 DERIVATIVES OF PIPERIDINE ACILATED AS AGONISTS OF THE RECEIVER MELANOCORTINA-4 ECSP034751A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27225801P 2001-02-28 2001-02-28

Publications (1)

Publication Number Publication Date
ECSP034751A true ECSP034751A (en) 2003-10-28

Family

ID=34078835

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP034751 ECSP034751A (en) 2001-02-28 2003-08-27 DERIVATIVES OF PIPERIDINE ACILATED AS AGONISTS OF THE RECEIVER MELANOCORTINA-4

Country Status (2)

Country Link
EC (1) ECSP034751A (en)
ZA (1) ZA200306160B (en)

Also Published As

Publication number Publication date
ZA200306160B (en) 2004-07-21

Similar Documents

Publication Publication Date Title
IS2474B (en) Acylated piperidine derivatives as melanocortin-4 receptor agonists
MXPA04000625A (en) Substituted piperidines as modulators of the melanocortin receptor.
ATE430565T1 (en) ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS
ATE411021T1 (en) BRIDGED PIPERIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS
EP1610789A4 (en) BICYCLIC PIPERIDINE DERIVATIVES AS AGONISTS OF MELANOCORTIN RECEPTOR 4
TW200508223A (en) Acylated piperazine derivatives as melanocortin-4 receptor agonists
MXPA05010724A (en) Acylated spiropiperidine derivatives as melanocortin-4 receptor agonists.
WO2002068387A3 (en) Acylated piperidine derivatives as melanocortin-4 receptor agonists
WO2002059107A8 (en) Substituted piperidines/piperazines as melanocortin receptor agonists
ES2318119T3 (en) PROCEDURE AND COMPOSITIONS TO ALTER THE PROFILE OF THE EDUCATING EFFECT OF LA SUCRALOSA.
WO2005009950A3 (en) Piperidine derivatives as melanocortin-4 receptor agonists
GT200300045A (en) NEW DERIVATIVES OF TIAZOL AS ANTAGONISTS OF THE NPY RECEIVER
WO2007041061A3 (en) Acylated piperidine derivatives as melanocortin-4 receptor agonists
GT200600422A (en) CARBOXAMIDE DERIVATIVES AS ANTAGONISTS OF THE MUSCARINIC RECEIVER
ES2132401T3 (en) TETRAHIDRO-1H-BENZAZEPINONAS AND HEXAHIDROAZEPINONAS AS SELECTIVE ANTAGONISTS OF THE COLLECTOSTOKININ-B RECEPTOR.
ATE454148T1 (en) ACYLATED PIPERIDED DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS
ECSP034751A (en) DERIVATIVES OF PIPERIDINE ACILATED AS AGONISTS OF THE RECEIVER MELANOCORTINA-4
BR0214613A (en) N-ureide piperidines as ccr-3 receptor antagonists
WO2006019787A3 (en) Acylated piperidine derivatives as melanocortin-4 receptor agonists
JO2351B1 (en) Acylated piperidine derivatives as melanocortin-4 receptor agonists
WO2009009292A3 (en) Crystalline forms of naltrexone methobromide
ECSP992985A (en) ADRENERGIC RECEPTOR COMPOUNDS ß-2