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Priority to ECSP003821priorityCriticalpatent/ECSP003821A/en
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
La presente invención describe compuestos de la fórmula I (gráfico), y enantiómeros, diastereómeros y sales farmacéuticamente aceptables de los mismos. Los compuestos de la fórmula I son inhibidores de la proteína cinasas y son útiles en el tratamiento de enfermedades proliferativas, por ejemplo, cáncer, inflamación y artritis. También pueden ser útiles en el tratamiento de la enfermedad del Alzheimer, alopecia inducida por quimioterapia y enfermedad cardiovascular.The present invention describes compounds of the formula I (graph), and enantiomers, diastereomers and pharmaceutically acceptable salts thereof. The compounds of the formula I are protein kinase inhibitors and are useful in the treatment of proliferative diseases, for example, cancer, inflammation and arthritis. They may also be useful in the treatment of Alzheimer's disease, chemotherapy-induced alopecia and cardiovascular disease.
ECSP0038212000-12-112000-12-11
INHIBITORS OF N- (5 (((5-ALQUIL-2-OXAZOLIL) METHYL) TIO) -2-TIAZOLIL) -CARBOXAMIDE OF CYCLINE-DEPENDENT KINASES
ECSP003821A
(en)