ECSP003786A - RANGE-HYDROXIL-2 (FLUOROALQUILOAMINOCARBONIL) -1-PIPERACINAPENTANAMIDAS AND USES OF THEM - Google Patents

RANGE-HYDROXIL-2 (FLUOROALQUILOAMINOCARBONIL) -1-PIPERACINAPENTANAMIDAS AND USES OF THEM

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Publication number
ECSP003786A
ECSP003786A ECSP003786A ECSP003786A EC SP003786 A ECSP003786 A EC SP003786A EC SP003786 A ECSP003786 A EC SP003786A EC SP003786 A ECSP003786 A EC SP003786A
Authority
EC
Ecuador
Prior art keywords
treatment
compounds
hiv
aids
inhibitors
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Subharekha Raghavan
James R Tata
Yuan Cheng
Brian Anthony Kirk
Kevin T Chapman
Nancy J Kevin
Joseph Leslie Duffy
Thomas A Rano
Tracy Huening
Fred J Fleitz
Daniel E Petrillo
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ECSP003786A publication Critical patent/ECSP003786A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Los compuestos y Hidroxi-2-(fluoroalquiloaminocarbonil)-1-piperacinapentanamida son inhibidores de la proteasa VIH e inhibidores de la replicación VIH. Estos compuestos son útiles en la prevención o tratamiento de la infección por VIH y en el tratamiento del SIDA, sea como compuestos, sales farmacéuticamente aceptables, ingredientes de composiciones farmacéuticas, o bien en combinación con otros antivirales inmunomoduladores antibióticos o vacunas. Los métodos para el tratamiento del SIDA y métodos para la prevención o tratamiento de la infección por VIH son igualmente descritos. Estos compuestos son efectivos en contra de mutantes virales VIH que son resistentes a inhibidores de proteasa que, en la actualidad, se utilizan para el tratamiento del SIDA y la infección por VIH.The compounds and Hydroxy-2- (fluoroalkyloaminocarbonyl) -1-piperazinepentanamide are inhibitors of the HIV protease and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of HIV infection and in the treatment of AIDS, whether as compounds, pharmaceutically acceptable salts, ingredients of pharmaceutical compositions, or in combination with other antibiotic immunomodulatory antivirals or vaccines. The methods for the treatment of AIDS and methods for the prevention or treatment of HIV infection are also described. These compounds are effective against HIV viral mutants that are resistant to protease inhibitors that are currently used for the treatment of AIDS and HIV infection.

ECSP003786 1999-11-24 2000-11-24 RANGE-HYDROXIL-2 (FLUOROALQUILOAMINOCARBONIL) -1-PIPERACINAPENTANAMIDAS AND USES OF THEM ECSP003786A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16747899P 1999-11-24 1999-11-24

Publications (1)

Publication Number Publication Date
ECSP003786A true ECSP003786A (en) 2002-03-25

Family

ID=40410317

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP003786 ECSP003786A (en) 1999-11-24 2000-11-24 RANGE-HYDROXIL-2 (FLUOROALQUILOAMINOCARBONIL) -1-PIPERACINAPENTANAMIDAS AND USES OF THEM

Country Status (1)

Country Link
EC (1) ECSP003786A (en)

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