ECSP003625A - HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALOPROTEINASE INHIBITORS - Google Patents

HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALOPROTEINASE INHIBITORS

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Publication number
ECSP003625A
ECSP003625A ECSP003625A ECSP003625A EC SP003625 A ECSP003625 A EC SP003625A EC SP003625 A ECSP003625 A EC SP003625A EC SP003625 A ECSP003625 A EC SP003625A
Authority
EC
Ecuador
Prior art keywords
diseases
compounds
methods
acid compounds
compounds useful
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Christopher Alan Conrad
Patrick Michael O'brien
Daniel Fred Ortwine
Joseph Armand Picard
Drago Robert Sliskovic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP003625 priority Critical patent/ECSP003625A/en
Publication of ECSP003625A publication Critical patent/ECSP003625A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Los compuestos de la fórmula (gráfico), son útiles para inhibir las enzimas de metaloproteinasa de matriz en animales, y evita y trata las enfermedades que resultan de la quebradura de tejidos conectivos. Además se decsriben métodos para la preparación de tales compuestos, composiciones farmacéuticas incluyendolos, y métodos de tratamiento de enfermedades en los cuales las metaloproteinasas de matriz son involucradas incluyendo la esclerosis múltiple la ruptura de placa de la arteriosclerosis, la restenosis, la aneurisma aórtica, la cardiopatías, las enfermedades periodontales, úlcera de cérnea, quemaduras, úlceras decubial, úlceras o heridas crónicas, metástasis de cáncer, angiogénesis de tumor, osteoporosis, reuma o osteoartritis enfermedad renal, dilatación ventricular izquierda, u otras enfermedades autoinmune o inflamatorias de la invención de leucocitos en el tejido.The compounds of the formula (graph) are useful for inhibiting matrix metalloproteinase enzymes in animals, and prevents and treats diseases resulting from breakdown of connective tissues. In addition, methods for the preparation of such compounds are described, including pharmaceutical compositions, and methods of treating diseases in which matrix metalloproteinases are involved including multiple sclerosis, rupture of arteriosclerosis plaque, restenosis, aortic aneurysm, heart disease, periodontal diseases, corneal ulcer, burns, decubial ulcers, chronic ulcers or wounds, cancer metastases, tumor angiogenesis, osteoporosis, rheumatism or osteoarthritis kidney disease, left ventricular dilation, or other autoimmune or inflammatory diseases of the invention of leukocytes in the tissue.

ECSP003625 2000-08-17 2000-08-17 HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALOPROTEINASE INHIBITORS ECSP003625A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP003625 ECSP003625A (en) 2000-08-17 2000-08-17 HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALOPROTEINASE INHIBITORS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP003625 ECSP003625A (en) 2000-08-17 2000-08-17 HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALOPROTEINASE INHIBITORS

Publications (1)

Publication Number Publication Date
ECSP003625A true ECSP003625A (en) 2000-11-24

Family

ID=42041230

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP003625 ECSP003625A (en) 2000-08-17 2000-08-17 HYDROXAMIC ACID COMPOUNDS USEFUL AS MATRIX METALOPROTEINASE INHIBITORS

Country Status (1)

Country Link
EC (1) ECSP003625A (en)

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