EA202192937A1 - MODULATING T-CELLS MULTIMERIC POLYPEPTIDES AND METHODS OF THEIR APPLICATION - Google Patents

MODULATING T-CELLS MULTIMERIC POLYPEPTIDES AND METHODS OF THEIR APPLICATION

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Publication number
EA202192937A1
EA202192937A1 EA202192937A EA202192937A EA202192937A1 EA 202192937 A1 EA202192937 A1 EA 202192937A1 EA 202192937 A EA202192937 A EA 202192937A EA 202192937 A EA202192937 A EA 202192937A EA 202192937 A1 EA202192937 A1 EA 202192937A1
Authority
EA
Eurasian Patent Office
Prior art keywords
modulating
cells
methods
application
multimeric polypeptides
Prior art date
Application number
EA202192937A
Other languages
Russian (ru)
Inventor
Сасо Семерски
Аниш Сури
Original Assignee
Кью Биофарма, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Кью Биофарма, Инк. filed Critical Кью Биофарма, Инк.
Priority claimed from PCT/US2020/034939 external-priority patent/WO2020243315A1/en
Publication of EA202192937A1 publication Critical patent/EA202192937A1/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

В данном изобретении предложены модулирующие Т-клетки мультимерные полипептиды, которые содержат иммуномодулирующий полипептид, эпитоп-презентирующий пептид и полипептиды ГКГС I класса. Модулирующий Т-клетки мультимерный полипептид пригоден для модуляции активности Т-клеток, а также для модуляции иммунного ответа у индивидуума.The present invention provides multimeric T-cell modulating polypeptides that comprise an immunomodulatory polypeptide, an epitope-presenting peptide, and MHC class I polypeptides. The T cell modulating multimeric polypeptide is useful for modulating T cell activity as well as for modulating the immune response in an individual.

EA202192937A 2019-09-17 2020-05-28 MODULATING T-CELLS MULTIMERIC POLYPEPTIDES AND METHODS OF THEIR APPLICATION EA202192937A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962901538P 2019-09-17 2019-09-17
PCT/US2020/034939 WO2020243315A1 (en) 2019-05-29 2020-05-28 Multimeric t-cell modulatory polypeptides and methods of use thereof

Publications (1)

Publication Number Publication Date
EA202192937A1 true EA202192937A1 (en) 2022-01-26

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Family Applications (1)

Application Number Title Priority Date Filing Date
EA202192937A EA202192937A1 (en) 2019-09-17 2020-05-28 MODULATING T-CELLS MULTIMERIC POLYPEPTIDES AND METHODS OF THEIR APPLICATION

Country Status (1)

Country Link
EA (1) EA202192937A1 (en)

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