EA202191499A1 - Системы и способы способствования клональной селекции - Google Patents
Системы и способы способствования клональной селекцииInfo
- Publication number
- EA202191499A1 EA202191499A1 EA202191499A EA202191499A EA202191499A1 EA 202191499 A1 EA202191499 A1 EA 202191499A1 EA 202191499 A EA202191499 A EA 202191499A EA 202191499 A EA202191499 A EA 202191499A EA 202191499 A1 EA202191499 A1 EA 202191499A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- image
- colony
- processor
- systems
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 238000009395 breeding Methods 0.000 title 1
- 230000001488 breeding effect Effects 0.000 title 1
- 230000001737 promoting effect Effects 0.000 title 1
- 238000013527 convolutional neural network Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/60—Type of objects
- G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
- G06V20/695—Preprocessing, e.g. image segmentation
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F18/00—Pattern recognition
- G06F18/20—Analysing
- G06F18/24—Classification techniques
- G06F18/241—Classification techniques relating to the classification model, e.g. parametric or non-parametric approaches
- G06F18/2413—Classification techniques relating to the classification model, e.g. parametric or non-parametric approaches based on distances to training or reference patterns
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N3/00—Computing arrangements based on biological models
- G06N3/02—Neural networks
- G06N3/04—Architecture, e.g. interconnection topology
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V10/00—Arrangements for image or video recognition or understanding
- G06V10/70—Arrangements for image or video recognition or understanding using pattern recognition or machine learning
- G06V10/764—Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V10/00—Arrangements for image or video recognition or understanding
- G06V10/70—Arrangements for image or video recognition or understanding using pattern recognition or machine learning
- G06V10/82—Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/60—Type of objects
- G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
- G06V20/693—Acquisition
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/60—Type of objects
- G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
- G06V20/698—Matching; Classification
Landscapes
- Engineering & Computer Science (AREA)
- Theoretical Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Multimedia (AREA)
- Life Sciences & Earth Sciences (AREA)
- Evolutionary Computation (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Artificial Intelligence (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Data Mining & Analysis (AREA)
- Software Systems (AREA)
- Computing Systems (AREA)
- Databases & Information Systems (AREA)
- Medical Informatics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Biophysics (AREA)
- Computational Linguistics (AREA)
- Mathematical Physics (AREA)
- Image Processing (AREA)
- Image Analysis (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
Способ способствования клональной селекции включает генерирование изображений временной последовательности лунки, содержащей среду, содержащих первое изображение и более позднее второе изображение. Способ также включает обнаружение одним или несколькими процессорами, анализирующими первое изображение, одного или нескольких объектов-кандидатов, изображенных на первом изображении, и для каждого из объектов-кандидатов определение того, является ли объект одиночной клеткой, путем анализа изображения объекта с использованием сверточной нейронной сети. Способ дополнительно включает обнаружение путем анализа второго изображения процессором (процессорами) колонии клеток, изображенной на втором изображении, и определение процессором (процессорами) того, была ли колония образована только из одной клетки, по меньшей мере частично на основании того, был ли каждый объект-кандидат определен в качестве одиночной клетки. Способ дополнительно включает генерирование процессором (процессорами) выходных данных, указывающих на то, была ли колония образована только из одной клетки.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862774154P | 2018-11-30 | 2018-11-30 | |
PCT/US2019/063177 WO2020112723A1 (en) | 2018-11-30 | 2019-11-26 | Systems and methods for facilitating clone selection |
Publications (1)
Publication Number | Publication Date |
---|---|
EA202191499A1 true EA202191499A1 (ru) | 2021-08-20 |
Family
ID=68966014
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA202191499A EA202191499A1 (ru) | 2018-11-30 | 2019-11-26 | Системы и способы способствования клональной селекции |
Country Status (14)
Country | Link |
---|---|
US (1) | US20220012465A1 (ru) |
EP (1) | EP3888004A1 (ru) |
JP (1) | JP2022509201A (ru) |
KR (1) | KR20210099028A (ru) |
CN (1) | CN113168519A (ru) |
AU (1) | AU2019387079B2 (ru) |
BR (1) | BR112021010404A2 (ru) |
CA (1) | CA3120281A1 (ru) |
CL (1) | CL2021001409A1 (ru) |
EA (1) | EA202191499A1 (ru) |
IL (1) | IL283577A (ru) |
MX (1) | MX2021005938A (ru) |
SG (1) | SG11202105399RA (ru) |
WO (1) | WO2020112723A1 (ru) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3173976A1 (en) | 2020-03-06 | 2021-09-10 | Amgen Inc. | Systems and methods for assessing cell growth rates |
US20220327863A1 (en) * | 2021-04-12 | 2022-10-13 | Bitsensing Inc. | Face identification using millimeter-wave radar sensor data |
WO2024161784A1 (ja) * | 2023-01-30 | 2024-08-08 | 富士フイルム株式会社 | 判定支援装置、判定支援装置の作動方法、および判定支援装置の作動プログラム |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19616997A1 (de) * | 1996-04-27 | 1997-10-30 | Boehringer Mannheim Gmbh | Verfahren zur automatisierten mikroskopunterstützten Untersuchung von Gewebeproben oder Körperflüssigkeitsproben |
US6753161B2 (en) * | 1997-03-27 | 2004-06-22 | Oncosis Llc | Optoinjection methods |
JPWO2011016189A1 (ja) * | 2009-08-07 | 2013-01-10 | 株式会社ニコン | 細胞の分類手法、この手法を用いた画像処理プログラム及び画像処理装置、並びに細胞塊の製造方法 |
EP2682187B1 (en) * | 2012-07-02 | 2017-09-13 | Molecular Devices, LLC | Selection method and apparatus |
EP2708890B1 (en) * | 2012-09-14 | 2015-11-18 | Molecular Devices (New Milton) Ltd | Method of selecting a monoclonal cell colony |
US9619881B2 (en) * | 2013-09-26 | 2017-04-11 | Cellogy, Inc. | Method and system for characterizing cell populations |
WO2015080001A1 (ja) * | 2013-11-27 | 2015-06-04 | 大日本印刷株式会社 | 培地情報登録システム、コロニー検出装置、プログラム及び衛生管理システム |
SI3304037T1 (sl) * | 2015-06-02 | 2020-03-31 | Baxalta Incorporated | Postopek za odbiranje kolonije celic |
WO2018213709A1 (en) * | 2017-05-19 | 2018-11-22 | Thrive Bioscience, Inc. | Systems and methods for counting cells |
GB2576191B (en) * | 2018-08-08 | 2022-11-16 | Sphere Fluidics Ltd | Droplet processing methods and systems |
-
2019
- 2019-11-26 EA EA202191499A patent/EA202191499A1/ru unknown
- 2019-11-26 JP JP2021529789A patent/JP2022509201A/ja active Pending
- 2019-11-26 KR KR1020217019305A patent/KR20210099028A/ko unknown
- 2019-11-26 AU AU2019387079A patent/AU2019387079B2/en active Active
- 2019-11-26 WO PCT/US2019/063177 patent/WO2020112723A1/en active Application Filing
- 2019-11-26 SG SG11202105399RA patent/SG11202105399RA/en unknown
- 2019-11-26 CA CA3120281A patent/CA3120281A1/en active Pending
- 2019-11-26 US US17/296,570 patent/US20220012465A1/en active Pending
- 2019-11-26 CN CN201980077951.XA patent/CN113168519A/zh active Pending
- 2019-11-26 MX MX2021005938A patent/MX2021005938A/es unknown
- 2019-11-26 EP EP19824078.0A patent/EP3888004A1/en active Pending
- 2019-11-26 BR BR112021010404-6A patent/BR112021010404A2/pt unknown
-
2021
- 2021-05-28 CL CL2021001409A patent/CL2021001409A1/es unknown
- 2021-05-30 IL IL283577A patent/IL283577A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CL2021001409A1 (es) | 2021-11-12 |
KR20210099028A (ko) | 2021-08-11 |
CN113168519A (zh) | 2021-07-23 |
SG11202105399RA (en) | 2021-06-29 |
CA3120281A1 (en) | 2020-06-04 |
MX2021005938A (es) | 2021-06-30 |
EP3888004A1 (en) | 2021-10-06 |
IL283577A (en) | 2021-07-29 |
JP2022509201A (ja) | 2022-01-20 |
WO2020112723A1 (en) | 2020-06-04 |
AU2019387079B2 (en) | 2024-08-01 |
BR112021010404A2 (pt) | 2021-08-24 |
US20220012465A1 (en) | 2022-01-13 |
AU2019387079A1 (en) | 2021-06-03 |
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