EA202191384A1 - 3,3-DIFLUORALLYLAMINES OR THEIR SALTS AND THEIR PHARMACEUTICAL COMPOSITIONS - Google Patents

3,3-DIFLUORALLYLAMINES OR THEIR SALTS AND THEIR PHARMACEUTICAL COMPOSITIONS

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Publication number
EA202191384A1
EA202191384A1 EA202191384A EA202191384A EA202191384A1 EA 202191384 A1 EA202191384 A1 EA 202191384A1 EA 202191384 A EA202191384 A EA 202191384A EA 202191384 A EA202191384 A EA 202191384A EA 202191384 A1 EA202191384 A1 EA 202191384A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutical compositions
difluorallylamines
salts
difluoroallylamines
pharmaceutically acceptable
Prior art date
Application number
EA202191384A
Other languages
Russian (ru)
Inventor
Тэ Дун Хан
Хи Цзэ Так
Юн Кюн Ким
Юй Чул Ли
Сол Парк
Хёк Цзун Чо
Чёл Хи Лим
Со Янг Ким
Хюн Хо Чой
Да На Цзён
На Йон Янг
На Ри Ха
Original Assignee
Юхань Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Юхань Корпорейшн filed Critical Юхань Корпорейшн
Priority claimed from PCT/IB2019/060736 external-priority patent/WO2020121261A1/en
Publication of EA202191384A1 publication Critical patent/EA202191384A1/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Изобретение относится к 3,3-дифтораллиламинам или их фармацевтически приемлемым солям, способам их получения, содержащим их фармацевтическим композициям и их применению. 3,3-Дифтораллиламины или их фармацевтически приемлемые соли проявляют сильную ингибирующую активность в отношении VAP-1 и, следовательно, могут быть с пользой применены, например, для лечения и профилактики неалкогольного гепатостеатоза (НАСГ).The invention relates to 3,3-difluoroallylamines or their pharmaceutically acceptable salts, methods for their preparation, pharmaceutical compositions containing them and their use. 3,3-Difluoroallylamines or their pharmaceutically acceptable salts exhibit strong inhibitory activity against VAP-1 and, therefore, can be advantageously used, for example, for the treatment and prevention of non-alcoholic hepatosteatosis (NASH).

EA202191384A 2019-10-31 2019-12-12 3,3-DIFLUORALLYLAMINES OR THEIR SALTS AND THEIR PHARMACEUTICAL COMPOSITIONS EA202191384A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20190137387 2019-10-31
PCT/IB2019/060736 WO2020121261A1 (en) 2018-12-14 2019-12-12 3,3-difluoroallylamines or salts thereof and pharmaceutical compositions comprising the same

Publications (1)

Publication Number Publication Date
EA202191384A1 true EA202191384A1 (en) 2021-10-06

Family

ID=78572630

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202191384A EA202191384A1 (en) 2019-10-31 2019-12-12 3,3-DIFLUORALLYLAMINES OR THEIR SALTS AND THEIR PHARMACEUTICAL COMPOSITIONS

Country Status (1)

Country Link
EA (1) EA202191384A1 (en)

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