EA202191282A1 - METHODS AND SYSTEM FOR ESTABLISHING RELATIONSHIP BETWEEN REDUCTION OF CHEMICALS AND CORRESPONDING GENETIC, MEDICAL AND / OR PATHOLOGICAL CONDITIONS - Google Patents
METHODS AND SYSTEM FOR ESTABLISHING RELATIONSHIP BETWEEN REDUCTION OF CHEMICALS AND CORRESPONDING GENETIC, MEDICAL AND / OR PATHOLOGICAL CONDITIONSInfo
- Publication number
- EA202191282A1 EA202191282A1 EA202191282A EA202191282A EA202191282A1 EA 202191282 A1 EA202191282 A1 EA 202191282A1 EA 202191282 A EA202191282 A EA 202191282A EA 202191282 A EA202191282 A EA 202191282A EA 202191282 A1 EA202191282 A1 EA 202191282A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- voc
- target cells
- cultures
- treatment
- mcd
- Prior art date
Links
Abstract
Способ определения действенности выбранной схемы лечения, назначенной пациенту, который включает процедуры получения данных о выделениях VOC из культур целевых клеток до лечения и создания, с использованием выделений VOC из культур целевых клеток до лечения, VOC-профиля целевых клеток до лечения. Создание VOC-профиля MCD целевых клеток посредством (a) индуцирования MCD в культурах непролеченных целевых клеток, тем самым создавая культуры пост-MCD целевых клеток; и (b) получения данных о выделениях VOC из культур пост-MCD целевых клеток. Выбранную схему лечения применяют к культурам целевых клеток, получают данные о выделениях VOC-культур целевых клеток после лечения и определяют действенностью выбранной схемы лечения. Лечение признают эффективным в том случае, когда (a) значения концентрации, полученные с использованием данных о выделениях VOC из культур целевых клеток до лечения, VOC, связанных с использованием VOC-профиля целевых клеток до лечения, превышают значения концентрации, полученные с использованием данных о выделениях VOC-культур целевых клеток после лечения, VOC, связанных с использованием VOC-профиля целевых клеток до лечения; и (b) значения концентрации, полученные с использованием данных о выделениях VOC из культур целевых клеток после лечения, VOC, связанных с использованием VOC-профиля MCD целевых клеток, выделяемых культурами целевых клеток после лечения, превышают значения концентрации, полученные с использованием данных о выделениях VOC-культур целевых клеток до лечения, VOC, связанных с использованием VOC-профиля MCD целевых клеток, выделяемых культурами целевых клеток до лечения.A method for determining the efficacy of a selected treatment regimen assigned to a patient, which includes procedures for obtaining data on VOC secretions from cultures of target cells before treatment and creating, using VOC secretions from cultures of target cells before treatment, a VOC profile of target cells before treatment. Generating a VOC profile of MCD target cells by (a) inducing MCD in untreated target cell cultures, thereby creating post-MCD target cell cultures; and (b) obtaining data on VOC secretions from post-MCD cultures of target cells. The selected treatment regimen is applied to the cultures of the target cells, data on the secretions of VOC-cultures of the target cells after treatment are obtained, and the efficacy of the selected treatment regimen is determined. Treatment is considered effective when (a) concentration values obtained using data on VOC excretion from cultures of target cells before treatment, VOCs associated with the use of VOC-profile of target cells before treatment exceed concentration values obtained using data on isolation of VOC-cultures of target cells after treatment, VOC associated with the use of VOC-profile of target cells before treatment; and (b) the concentration values obtained using the VOC excretion data from the target cell cultures after treatment, the VOCs associated with the use of the MCD VOC profile of the target cells recovered by the target cell cultures after treatment are higher than the concentration values obtained using the excretion data VOC-cultures of target cells before treatment, VOC-associated using the VOC-profile of MCD target cells, isolated by cultures of target cells before treatment.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962929882P | 2019-11-03 | 2019-11-03 | |
| PCT/IL2019/051208 WO2020089923A1 (en) | 2018-11-04 | 2019-11-04 | Methods and system for associating between discharge of chemicals, and corresponding genetic, medical and/or pathological conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA202191282A1 true EA202191282A1 (en) | 2021-07-26 |
Family
ID=77443289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA202191282A EA202191282A1 (en) | 2019-11-03 | 2019-11-04 | METHODS AND SYSTEM FOR ESTABLISHING RELATIONSHIP BETWEEN REDUCTION OF CHEMICALS AND CORRESPONDING GENETIC, MEDICAL AND / OR PATHOLOGICAL CONDITIONS |
Country Status (1)
| Country | Link |
|---|---|
| EA (1) | EA202191282A1 (en) |
-
2019
- 2019-11-04 EA EA202191282A patent/EA202191282A1/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2022009242A (en) | Alignment and variant sequencing analysis pipeline. | |
| CY1123254T1 (en) | METHODS FOR CELL TRANSFORMATION AND PROCESSING | |
| EA202091673A1 (en) | METHOD FOR AMPLIFICATION OF NUCLEIC ACIDS | |
| EA201991556A1 (en) | PHOSPHODIESTHESIS INHIBITORS AND METHODS FOR TREATING MICROBIAL INFECTION | |
| DE602004028590D1 (en) | Device for recovering the aortic valve and this treatment method | |
| DK1599575T3 (en) | Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions | |
| WO2016201450A3 (en) | Cancer treatment and diagnosis | |
| DK1885382T3 (en) | Methods for using adipose tissue-derived cells in the treatment of cardiovascular conditions | |
| CL2020002161A1 (en) | Compositions and Methods for Treating Non-Age-Related Hearing Impairment in a Human Subject. | |
| WO2021231237A3 (en) | Antibodies for sars-cov-2 and uses thereof | |
| EA202191508A1 (en) | REPRODUCTION OF NATURAL KILLER CELLS AND ILC3 CELLS USING NEW AROMATIC COMPOUNDS | |
| EA201691094A1 (en) | OBTAINING ANTIBODIES FOR CONJUGATION FROM CHO CELL CULTURES | |
| EA201792538A1 (en) | METHOD OF BIOLOGICAL OBTAINING OF METACRYLIC ACID | |
| MX2022014741A (en) | METHODS FOR DETECTING<i> BORDETELLA. | |
| EA202190474A1 (en) | MICRO-RNA THERAPY AGAINST LCP-1-POSITIVE TUMORS | |
| PH12019550022A1 (en) | Anti-ageing pharmaceutical preparation | |
| EA201591522A1 (en) | TREATMENT OF THE TRANSPLANTATE REACTIONS AGAINST THE OWNER OF THE EXPOSED PATIENT TRANSPLANTATION | |
| EA202191282A1 (en) | METHODS AND SYSTEM FOR ESTABLISHING RELATIONSHIP BETWEEN REDUCTION OF CHEMICALS AND CORRESPONDING GENETIC, MEDICAL AND / OR PATHOLOGICAL CONDITIONS | |
| AR121390A1 (en) | COMPOSITIONS AND METHODS FOR TREATING NON-AGE RELATED HEARING IMPAIRMENT IN A HUMAN SUBJECT | |
| MX2021009862A (en) | Methods for obtaining induced smooth muscle cells. | |
| MX2021009247A (en) | Methods, systems, and kits for treating inflammatory disease targeting il18r1. | |
| BR112018014762A2 (en) | method of treating (early) alzheimer's disease | |
| EA201792603A1 (en) | ANGIOGENESIS USING STIMULATED PLACENTAL STEM CELLS | |
| EA202091732A1 (en) | NUCLEIC ACID CONSTRUCTIONS AND VACCINES FROM LARGE AND SMALL T-ANTIGENS OF POLIOMAVIRUS OF MERCKEL CELLS AND METHODS OF THEIR APPLICATION | |
| MX2020007619A (en) | Targeted interventions directed at reducing the levels of circulating succinate in a subject, and kits and method for determining effectiveness of said interventions. |