EA202092864A1 - PHARMACEUTICAL COMPOSITION FOR PARENTERAL DROP INJECTION - Google Patents

PHARMACEUTICAL COMPOSITION FOR PARENTERAL DROP INJECTION

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Publication number
EA202092864A1
EA202092864A1 EA202092864A EA202092864A EA202092864A1 EA 202092864 A1 EA202092864 A1 EA 202092864A1 EA 202092864 A EA202092864 A EA 202092864A EA 202092864 A EA202092864 A EA 202092864A EA 202092864 A1 EA202092864 A1 EA 202092864A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutical composition
parenteral
acid
asparaginate
drop injection
Prior art date
Application number
EA202092864A
Other languages
Russian (ru)
Inventor
Виктор Александрович Сисев
Original Assignee
Общество с ограниченной ответственностью "Ай Кью Витаминная студия"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Общество с ограниченной ответственностью "Ай Кью Витаминная студия" filed Critical Общество с ограниченной ответственностью "Ай Кью Витаминная студия"
Publication of EA202092864A1 publication Critical patent/EA202092864A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0029—Parenteral nutrition; Parenteral nutrition compositions as drug carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Изобретение относится к области фармацевтической промышленности, а именно к фармацевтической композиции для парентерального капельного введения для применения при перенапряжении в условиях интенсивных нагрузок, характеризующейся тем, что содержит комплекс активных веществ при следующем соотношении компонентов: флавинадениндинуклеотид натрия - 40 мг; никотинамидадениндинуклеотидфосфат - 500 мг; фолиевая кислота - 15 мг; кальция фолинат пентагидрат - 50 мг; цианокобаламин - 1 мг; метилкобаламин - 500 мкг; глутатион - 600-1200 мг; -липоевая (тиоктовая) кислота - 50 мг; -D-фруктозо-1,6-дифосфат - 5000-10000 мг; N,N-диметилглицин - 300 мг; аскорбиновая кислота - 2000 мг; L-таурин - 500 мг; L-карнитин - 1000 мг; инозин - 400 мг; магния аспарагинат - 280 мг; калия аспарагинат - 320 мг; кальция глюконат - 500 мг; декстроза 5% - до 500 мл. Изобретение обеспечивает создание высокоэффективной лекарственной формы, которая может быть использована при различных состояниях, связанных с физическими перегрузками и перенапряжением отдельных органов и систем.The invention relates to the field of the pharmaceutical industry, namely to a pharmaceutical composition for parenteral drip administration for use in case of overexertion under conditions of intense stress, characterized by the fact that it contains a complex of active substances with the following ratio of components: sodium flavinadenine dinucleotide - 40 mg; nicotinamide adenine dinucleotide phosphate - 500 mg; folic acid - 15 mg; calcium folinate pentahydrate - 50 mg; cyanocobalamin - 1 mg; methylcobalamin - 500 mcg; glutathione - 600-1200 mg; -lipoic (thioctic) acid - 50 mg; -D-fructose-1,6-diphosphate - 5000-10000 mg; N, N-dimethylglycine - 300 mg; ascorbic acid - 2000 mg; L-taurine - 500 mg; L-carnitine - 1000 mg; inosine - 400 mg; magnesium asparaginate - 280 mg; potassium asparaginate - 320 mg; calcium gluconate - 500 mg; dextrose 5% - up to 500 ml. The invention provides the creation of a highly effective dosage form that can be used in various conditions associated with physical overload and overstrain of individual organs and systems.

EA202092864A 2019-12-25 2020-12-23 PHARMACEUTICAL COMPOSITION FOR PARENTERAL DROP INJECTION EA202092864A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2019143808A RU2723950C1 (en) 2019-12-25 2019-12-25 Pharmaceutical composition for parenteral drop introduction

Publications (1)

Publication Number Publication Date
EA202092864A1 true EA202092864A1 (en) 2021-06-30

Family

ID=71096163

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202092864A EA202092864A1 (en) 2019-12-25 2020-12-23 PHARMACEUTICAL COMPOSITION FOR PARENTERAL DROP INJECTION

Country Status (2)

Country Link
EA (1) EA202092864A1 (en)
RU (1) RU2723950C1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2747890C1 (en) * 2021-03-24 2021-05-17 Общество С Ограниченной Ответственностью "Ива Фарм" Agent for reducing risk and relieving symptoms of beta-coronavirus infection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019099731A1 (en) * 2017-11-15 2019-05-23 Activate Bio Physics Corp. Formulations and dosage forms for enhancing performance or recovery from stress
RU2707948C1 (en) * 2019-09-02 2019-12-02 Виктор Александрович Сисев Pharmaceutical composition for parenteral drip introduction (versions)
RU2709500C1 (en) * 2019-10-15 2019-12-18 Виктор Александрович Сисев Pharmaceutical composition for parenteral drip introduction

Also Published As

Publication number Publication date
RU2723950C1 (en) 2020-06-18

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