EA202092463A1 - Angiotensin II, alone or in combination for the treatment of hypotension - Google Patents
Angiotensin II, alone or in combination for the treatment of hypotensionInfo
- Publication number
- EA202092463A1 EA202092463A1 EA202092463A EA202092463A EA202092463A1 EA 202092463 A1 EA202092463 A1 EA 202092463A1 EA 202092463 A EA202092463 A EA 202092463A EA 202092463 A EA202092463 A EA 202092463A EA 202092463 A1 EA202092463 A1 EA 202092463A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- angiotensin
- dose
- norepinephrine
- treatment
- hypotension
- Prior art date
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Изобретение относится, например, к способу, включающему введение субъекту, испытывающему интенсивный шок и получающему лечение катехоламином в дозе, эквивалентной по меньшей мере примерно 0,2 мкг/кг/мин норадреналина, дозы ангиотензина II, которая эффективна для повышения кровяного давления субъекта до уровня среднего артериального давления (САД) примерно 65 мм рт. ст. или выше, и которая эффективна для снижения дозы катехоламина, необходимой для поддержания САД на уровне примерно 65 мм рт. ст., до дозы, эквивалентной примерно 0,05-2,0 мкг/кг/мин норадреналина или менее, или до дозы, эквивалентной примерно 0,05 мкг/кг/мин норадреналина или менее.The invention relates, for example, to a method comprising administering to a subject in severe shock and receiving treatment with catecholamine at a dose equivalent to at least about 0.2 μg / kg / min of norepinephrine, a dose of angiotensin II that is effective to raise the subject's blood pressure to a level mean arterial pressure (MAP) approximately 65 mm Hg. Art. or higher, and which is effective in reducing the dose of catecholamine required to maintain SBP at about 65 mmHg. Art., to a dose equivalent to about 0.05-2.0 μg / kg / min of norepinephrine or less, or to a dose equivalent to about 0.05 μg / kg / min of norepinephrine or less.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461955706P | 2014-03-19 | 2014-03-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA202092463A1 true EA202092463A1 (en) | 2021-10-29 |
Family
ID=78572579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA202092463A EA202092463A1 (en) | 2014-03-19 | 2014-12-18 | Angiotensin II, alone or in combination for the treatment of hypotension |
Country Status (1)
| Country | Link |
|---|---|
| EA (1) | EA202092463A1 (en) |
-
2014
- 2014-12-18 EA EA202092463A patent/EA202092463A1/en unknown
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