EA202092110A1 - AMINO ACID COMPOUNDS AND METHODS OF APPLICATION - Google Patents

AMINO ACID COMPOUNDS AND METHODS OF APPLICATION

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Publication number
EA202092110A1
EA202092110A1 EA202092110A EA202092110A EA202092110A1 EA 202092110 A1 EA202092110 A1 EA 202092110A1 EA 202092110 A EA202092110 A EA 202092110A EA 202092110 A EA202092110 A EA 202092110A EA 202092110 A1 EA202092110 A1 EA 202092110A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
application
amino acid
acid compounds
formula
Prior art date
Application number
EA202092110A
Other languages
Russian (ru)
Inventor
Якоб Ча
Чэнго Дун
Тимоти Хом
Лань Цзян
Катерина Лефтерис
Хой Ли
мл. Дэвид Дж. Морганс
Мануэль Муньос
Морин Рейлли
Яцзюнь Чжэн
Original Assignee
Плайэнт Терапьютикс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Плайэнт Терапьютикс, Инк. filed Critical Плайэнт Терапьютикс, Инк.
Priority claimed from PCT/US2019/021243 external-priority patent/WO2019173653A1/en
Publication of EA202092110A1 publication Critical patent/EA202092110A1/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Данное изобретение относится к соединениям формулы (А) и формулы (I)или к их солям, где R1, R2, R10, R11, R12, R13, R14, R15, R16, q и р являются такими, как описано в данном документе. Соединения формулы (A), формулы (I) и их фармацевтические композиции являются ингибиторами интегрина v6, которые пригодны для лечения фиброза, такого как идиопатический фиброз легких (IPF) и неспецифическая интерстициальная пневмония (NSIP).This invention relates to compounds of formula (A) and formula (I) or salts thereof, wherein R1, R2, R10, R11, R12, R13, R14, R15, R16, q and p are as described herein. The compounds of formula (A), formula (I) and pharmaceutical compositions thereof are inhibitors of v6 integrin which are useful in the treatment of fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

EA202092110A 2018-06-27 2019-03-07 AMINO ACID COMPOUNDS AND METHODS OF APPLICATION EA202092110A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862690933P 2018-06-27 2018-06-27
PCT/US2019/021243 WO2019173653A1 (en) 2018-03-07 2019-03-07 Amino acid compounds and methods of use

Publications (1)

Publication Number Publication Date
EA202092110A1 true EA202092110A1 (en) 2021-02-15

Family

ID=74855473

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202092110A EA202092110A1 (en) 2018-06-27 2019-03-07 AMINO ACID COMPOUNDS AND METHODS OF APPLICATION

Country Status (1)

Country Link
EA (1) EA202092110A1 (en)

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