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Application filed by Эли Лилли Энд КомпаниfiledCriticalЭли Лилли Энд Компани
Priority claimed from PCT/US2019/019074external-prioritypatent/WO2019168744A1/en
Publication of EA202091821A1publicationCriticalpatent/EA202091821A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
В данном изобретении предложены соединения 5-[5-[2-циклоалкил]-6-пиридазин-3-ил]-1H-пиримидин-2,4-диона или их фармацевтически приемлемые соли, которые ингибируют активность CD73 и пригодны для лечения рака.The present invention provides 5- [5- [2-cycloalkyl] -6-pyridazin-3-yl] -1H-pyrimidine-2,4-dione compounds, or pharmaceutically acceptable salts thereof, which inhibit CD73 activity and are useful in the treatment of cancer.