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Application filed by Суновион Фармасьютикалз Инк.filedCriticalСуновион Фармасьютикалз Инк.
Priority claimed from PCT/US2018/063859external-prioritypatent/WO2019113079A1/en
Publication of EA202091376A1publicationCriticalpatent/EA202091376A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Представлены композиции, включающие неравные смеси (R)-амисульприда и (S)-амисульприда или их фармацевтически приемлемые соли, где количество (R)-амисульприда больше, чем количество (S)-амисульприда, композиции и лекарственные средства, включающие такие смеси, применяемые для лечения различных заболеваний и расстройств, и способы с использованием вышеуказанных композиций для лечения различных заболеваний и расстройств, включая, но не ограничиваясь этим, дозовые режимы. Кроме того, представлены их различные лекарственные формы, включая, но не ограничиваясь этим, лекарственные формы с использованием полиморфов энантиомерного амисульприда.Presented are compositions comprising unequal mixtures of (R) -amisulpride and (S) -amisulpride, or pharmaceutically acceptable salts thereof, where the amount of (R) -amisulpride is greater than the amount of (S) -amisulpride, compositions and medicaments comprising such mixtures used for the treatment of various diseases and disorders, and methods using the above compositions for the treatment of various diseases and disorders, including, but not limited to, dosage regimens. In addition, various dosage forms are provided, including, but not limited to, dosage forms using polymorphs of the enantiomeric amisulpride.
EA202091376A2018-08-092018-12-04
NON-RACEMIC MIXTURES AND THEIR APPLICATIONS
EA202091376A1
(en)
7-BENZYL-4- (2-METHYLBENZIL) -2,4,6,7,8,9-HEXAHYDROIMIDAZO [1,2-A] PYRIDO [3,4-E] PYRIMIDIN-5 (1H) -OH, ITS ANALOGUES AND SALTS AND METHODS OF THEIR APPLICATION IN THERAPY
compound, composition, pharmaceutically acceptable salt of a compound, combination, pharmaceutical formulation, methods for killing a mycobacterium and / or inhibiting replication of disease causing mycobacteria in an animal, for treating a mycobacterial infection in an animal and for treating a disease resulting from a mycobacterial infection of a mammal, and use of a compound.