EA202090841A2 - MOLECULES BINDING WITH EGFR AND c-MET WITH TYPE III FIBRONECTIN DOMAINS - Google Patents

MOLECULES BINDING WITH EGFR AND c-MET WITH TYPE III FIBRONECTIN DOMAINS

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Publication number
EA202090841A2
EA202090841A2 EA202090841A EA202090841A EA202090841A2 EA 202090841 A2 EA202090841 A2 EA 202090841A2 EA 202090841 A EA202090841 A EA 202090841A EA 202090841 A EA202090841 A EA 202090841A EA 202090841 A2 EA202090841 A2 EA 202090841A2
Authority
EA
Eurasian Patent Office
Prior art keywords
egfr
met
type iii
molecules binding
fibronectin domains
Prior art date
Application number
EA202090841A
Other languages
Russian (ru)
Other versions
EA202090841A3 (en
Inventor
Марк Андерсон
Рикардо Аттар
Майкл Дим
Лайнус Хиун
Стивен ДЖЕКОБС
Аластэр Кинг
Донна Клейн
Шери Мурс
Карин О'Нил
Кристен Пича
Original Assignee
Янссен Байотек, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Янссен Байотек, Инк. filed Critical Янссен Байотек, Инк.
Publication of EA202090841A2 publication Critical patent/EA202090841A2/en
Publication of EA202090841A3 publication Critical patent/EA202090841A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Описаны моноспецифические и биспецифические молекулы, содержащие домены FN3, связывающиеся с EGFR и/или с-Met, выделенные нуклеотиды, кодирующие молекулы, векторы, клетки-хозяева и способы их получения. Данные моноспецифические и биспецифические молекулы, содержащие домены FN3, связывающиеся с EGFR и/или с-Met, подходят для создания терапевтических композиций для лечения и диагностики заболеваний и расстройств, включая рак.Described are monospecific and bispecific molecules containing FN3 domains that bind to EGFR and / or c-Met, isolated nucleotides encoding molecules, vectors, host cells and methods for their preparation. These monospecific and bispecific molecules containing FN3 domains that bind to EGFR and / or c-Met are suitable for creating therapeutic compositions for the treatment and diagnosis of diseases and disorders, including cancer.

EA202090841A 2013-04-08 2013-11-21 MOLECULES BINDING WITH EGFR AND C-MET WITH TYPE III FIBRONEKTIN DOMAINS EA202090841A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361809541P 2013-04-08 2013-04-08

Publications (2)

Publication Number Publication Date
EA202090841A2 true EA202090841A2 (en) 2020-07-31
EA202090841A3 EA202090841A3 (en) 2020-10-30

Family

ID=71833524

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202090841A EA202090841A3 (en) 2013-04-08 2013-11-21 MOLECULES BINDING WITH EGFR AND C-MET WITH TYPE III FIBRONEKTIN DOMAINS

Country Status (1)

Country Link
EA (1) EA202090841A3 (en)

Also Published As

Publication number Publication date
EA202090841A3 (en) 2020-10-30

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