EA202090575A3 - CONNECTIONS FOR POSITRON EMISSION TOMOGRAPHY - Google Patents
CONNECTIONS FOR POSITRON EMISSION TOMOGRAPHYInfo
- Publication number
- EA202090575A3 EA202090575A3 EA202090575A EA202090575A EA202090575A3 EA 202090575 A3 EA202090575 A3 EA 202090575A3 EA 202090575 A EA202090575 A EA 202090575A EA 202090575 A EA202090575 A EA 202090575A EA 202090575 A3 EA202090575 A3 EA 202090575A3
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- radionuclide
- positron emission
- emission tomography
- connections
- agent
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
В изобретении описаны соединения, композиции и способы для диагностирования и/или наблюдения патогенного заболевания с использованием позитронно-эмиссионной томографии. Кроме того, описаны конъюгаты формулы B-L-P, где B представляет собой радикал, представляющий собой средство нацеливания, выбранное из связывающихся с рецептором витамина лигандов, связывающихся с PSMA лигандов (таких как фолат), или ингибиторов PSMA, L представляет собой бивалентный линкер, содержащий аспарагиновую кислоту, лизин или агинин, и P представляет собой радикал, представляющий собой средство визуализации или средство лучевой терапии, такой как радионуклид или содержащая радионуклид группа, или радикал, представляющий собой соединение, способное к связыванию с радионуклидом или содержащей радионуклид группой, например металлохелатирующей группой.The invention describes compounds, compositions and methods for diagnosing and / or monitoring a pathogenic disease using positron emission tomography. In addition, conjugates of formula BLP are described wherein B is a targeting agent radical selected from vitamin receptor binding ligands, PSMA binding ligands (such as folate), or PSMA inhibitors, L is a bivalent linker containing aspartic acid , lysine or aginine, and P is a radical representing an imaging agent or a radiation therapy agent such as a radionuclide or a radionuclide-containing group, or a radical representing a compound capable of binding to a radionuclide or a radionuclide-containing group, for example a metal chelating group.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361909822P | 2013-11-27 | 2013-11-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA202090575A2 EA202090575A2 (en) | 2020-06-30 |
| EA202090575A3 true EA202090575A3 (en) | 2020-08-31 |
Family
ID=71138812
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA202090575A EA202090575A3 (en) | 2013-11-27 | 2014-11-13 | CONNECTIONS FOR POSITRON EMISSION TOMOGRAPHY |
Country Status (1)
| Country | Link |
|---|---|
| EA (1) | EA202090575A3 (en) |
-
2014
- 2014-11-13 EA EA202090575A patent/EA202090575A3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA202090575A2 (en) | 2020-06-30 |
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