EA202090549A1 - RESTORATION OF T-CELLS ACTIVITY THROUGH THE CD39 / CD73 SYSTEM - Google Patents

RESTORATION OF T-CELLS ACTIVITY THROUGH THE CD39 / CD73 SYSTEM

Info

Publication number
EA202090549A1
EA202090549A1 EA202090549A EA202090549A EA202090549A1 EA 202090549 A1 EA202090549 A1 EA 202090549A1 EA 202090549 A EA202090549 A EA 202090549A EA 202090549 A EA202090549 A EA 202090549A EA 202090549 A1 EA202090549 A1 EA 202090549A1
Authority
EA
Eurasian Patent Office
Prior art keywords
restoration
cells activity
treatment
cells
activity
Prior art date
Application number
EA202090549A
Other languages
Russian (ru)
Inventor
Стефани Шанто
Николя Гурден
Карин Патурель
Иван Перро
Бенжамин Росси
Original Assignee
Иннейт Фарма
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Иннейт Фарма filed Critical Иннейт Фарма
Priority claimed from PCT/EP2018/077217 external-priority patent/WO2019068907A1/en
Publication of EA202090549A1 publication Critical patent/EA202090549A1/en

Links

Abstract

В настоящем изобретении предложены способы применения соединений, которые ингибируют ферментативную активность растворимого CD39 человека, для лечения рака, включая, но не ограничиваясь, лечение типов рака, характеризуемых экспрессирующими CD73 клетками.The present invention provides methods of using compounds that inhibit the enzymatic activity of human soluble CD39 for the treatment of cancer, including, but not limited to, treatment of cancers characterized by CD73 expressing cells.

EA202090549A 2018-06-18 2018-10-05 RESTORATION OF T-CELLS ACTIVITY THROUGH THE CD39 / CD73 SYSTEM EA202090549A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862686143P 2018-06-18 2018-06-18
PCT/EP2018/077217 WO2019068907A1 (en) 2017-10-06 2018-10-05 Restoration of t cell activity via the cd39/cd73 axis

Publications (1)

Publication Number Publication Date
EA202090549A1 true EA202090549A1 (en) 2020-12-07

Family

ID=74100004

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202090549A EA202090549A1 (en) 2018-06-18 2018-10-05 RESTORATION OF T-CELLS ACTIVITY THROUGH THE CD39 / CD73 SYSTEM

Country Status (1)

Country Link
EA (1) EA202090549A1 (en)

Similar Documents

Publication Publication Date Title
PH12020500240A1 (en) Anti-cd39 antibodies, compositions comprising anti-cd39 antibodies and methods of using anti-cd39 antibodies
MX2020012797A (en) Anti-pvrig/anti-tigit bispecific antibodies and methods of use.
CO2018003500A2 (en) Anti-pd-1 antibodies and compositions
MX2019010848A (en) Compositions and methods for treating cancer.
PH12017502188A1 (en) Methods and compositions for inhibiting the interaction of menin with mll proteins
MX2017004691A (en) Cd73 blockade.
PH12017501483A1 (en) Bicyclic heterocycles as fgfr4 inhibitors
SG10201811841UA (en) Methods of treating cancer using tigit inhibitors and anti-cancer agents
EA201992610A1 (en) T-CELL EXPANSION, COMPOSITIONS AND WAYS OF THEIR APPLICATION
MX2022008523A (en) Glycan-interacting compounds and methods of use.
PH12019502025A1 (en) Anti-tigit antigen-binding proteins and methods of use thereof
EA201691845A1 (en) PHARMACEUTICAL COMPOSITIONS OF THERAPEUTICALLY ACTIVE COMPOUNDS
MX2022010638A (en) Pde9 inhibitors for treatment of peripheral diseases.
EA201691844A1 (en) PHARMACEUTICAL COMPOSITIONS OF THERAPEUTICALLY ACTIVE COMPOUNDS
EA201692100A1 (en) NEW ANTIBODIES AGAINST RNF43 AND METHODS OF THEIR APPLICATION
MX2022001310A (en) Phenyl-2-hydroxy-acetylamino-2-methyl-phenyl compounds.
WO2019090347A8 (en) Adenosine pathway inhibitors for cancer treatment
MX2023000191A (en) Methods of making and using pde9 inhibitors.
MX2022002682A (en) Anti-cd73 antibodies.
EP4275746A3 (en) Extracellular vesicles derived from osteoblastic lineage cells for therapeutic and diagnostic use
MX2020005640A (en) Humanized anti-liv1 antibodies for the treatment of breast cancer.
WO2018138032A3 (en) NKp46 BINDING AGENTS
EA202092518A1 (en) COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER
EA202090549A1 (en) RESTORATION OF T-CELLS ACTIVITY THROUGH THE CD39 / CD73 SYSTEM
MA43158B1 (en) Oxa-diazadispiro compounds with activity against pain