EA202090453A3 - ANTIBODIES TO CD40 - Google Patents

ANTIBODIES TO CD40

Info

Publication number
EA202090453A3
EA202090453A3 EA202090453A EA202090453A EA202090453A3 EA 202090453 A3 EA202090453 A3 EA 202090453A3 EA 202090453 A EA202090453 A EA 202090453A EA 202090453 A EA202090453 A EA 202090453A EA 202090453 A3 EA202090453 A3 EA 202090453A3
Authority
EA
Eurasian Patent Office
Prior art keywords
antibodies
fcriib
antigen
bind
administering
Prior art date
Application number
EA202090453A
Other languages
Russian (ru)
Other versions
EA202090453A2 (en
Inventor
Брайан С. Барнхарт
Бригитт Дево
Аарон П. Ямнюк
Шэннон Л. Окада
Бренда Л. Стивенс
Original Assignee
Бристол-Маерс Сквибб Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бристол-Маерс Сквибб Компани filed Critical Бристол-Маерс Сквибб Компани
Publication of EA202090453A2 publication Critical patent/EA202090453A2/en
Publication of EA202090453A3 publication Critical patent/EA202090453A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

В изобретении предоставлены агонистические антитела или их антигенсвязывающие части, которые связываются с CD40 человека. Такие антитела необязательно содержат Fc-области с увеличенной специфичностью к FcRIIb. Изобретение также относится к способам лечения злокачественной опухоли или хронической инфекции посредством введения нуждающемуся в этом индивидууму антител по изобретению.The invention provides agonist antibodies or antigen-binding portions thereof that bind to human CD40. Such antibodies optionally contain Fc regions with increased specificity for FcRIIb. The invention also relates to methods of treating cancer or chronic infection by administering to an individual in need of the antibodies of the invention.

EA202090453A 2015-11-09 2016-06-28 ANTIBODIES TO CD40 EA202090453A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562252615P 2015-11-09 2015-11-09

Publications (2)

Publication Number Publication Date
EA202090453A2 EA202090453A2 (en) 2020-06-30
EA202090453A3 true EA202090453A3 (en) 2020-09-30

Family

ID=71138781

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202090453A EA202090453A3 (en) 2015-11-09 2016-06-28 ANTIBODIES TO CD40

Country Status (1)

Country Link
EA (1) EA202090453A3 (en)

Also Published As

Publication number Publication date
EA202090453A2 (en) 2020-06-30

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