EA202090415A1 - ANTI-CD47 ANTIBODIES AND THEIR APPLICATION - Google Patents

ANTI-CD47 ANTIBODIES AND THEIR APPLICATION

Info

Publication number
EA202090415A1
EA202090415A1 EA202090415A EA202090415A EA202090415A1 EA 202090415 A1 EA202090415 A1 EA 202090415A1 EA 202090415 A EA202090415 A EA 202090415A EA 202090415 A EA202090415 A EA 202090415A EA 202090415 A1 EA202090415 A1 EA 202090415A1
Authority
EA
Eurasian Patent Office
Prior art keywords
antibodies
disease
application
arteriosclerosis
treating
Prior art date
Application number
EA202090415A
Other languages
Russian (ru)
Inventor
Минхань Ван
Хой Цзоу
Джошуа Оукс
Хайцюнь Цзя
Original Assignee
Фейнз Терапьютикс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фейнз Терапьютикс, Инк. filed Critical Фейнз Терапьютикс, Инк.
Priority claimed from PCT/US2018/044384 external-priority patent/WO2019027903A1/en
Publication of EA202090415A1 publication Critical patent/EA202090415A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Описаны анти-CD47 антитела и антигенсвязывающие фрагменты. Также описаны нуклеиновые кислоты, кодирующие эти антитела, композиции, содержащие антитела, и способы получения антител и применения антител для лечения или профилактики заболеваний, таких как злокачественная опухоль, воспалительное заболевание, инфекционное заболевание, артериосклероз, сердечно-сосудистое заболевание, нарушения метаболизма, радиационное поражение и/или аутоиммунное заболевание.Anti-CD47 antibodies and antigen binding fragments are described. Also described are nucleic acids encoding these antibodies, compositions containing antibodies, and methods for producing antibodies and using antibodies for treating or preventing diseases such as a malignant tumor, inflammatory disease, infectious disease, arteriosclerosis, cardiovascular disease, metabolic disorders, radiation damage and / or autoimmune disease.

EA202090415A 2018-04-13 2018-07-30 ANTI-CD47 ANTIBODIES AND THEIR APPLICATION EA202090415A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862657094P 2018-04-13 2018-04-13
PCT/US2018/044384 WO2019027903A1 (en) 2017-08-02 2018-07-30 Anti-cd47 antibodies and uses thereof

Publications (1)

Publication Number Publication Date
EA202090415A1 true EA202090415A1 (en) 2020-06-02

Family

ID=71138829

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202090415A EA202090415A1 (en) 2018-04-13 2018-07-30 ANTI-CD47 ANTIBODIES AND THEIR APPLICATION

Country Status (1)

Country Link
EA (1) EA202090415A1 (en)

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