EA202090225A3 - MODIFIED MENINGOCOCCAL FHBP POLYPEPTIDES - Google Patents

MODIFIED MENINGOCOCCAL FHBP POLYPEPTIDES

Info

Publication number
EA202090225A3
EA202090225A3 EA202090225A EA202090225A EA202090225A3 EA 202090225 A3 EA202090225 A3 EA 202090225A3 EA 202090225 A EA202090225 A EA 202090225A EA 202090225 A EA202090225 A EA 202090225A EA 202090225 A3 EA202090225 A3 EA 202090225A3
Authority
EA
Eurasian Patent Office
Prior art keywords
meningococcal fhbp
fhbp polypeptides
modified meningococcal
modified
polypeptides
Prior art date
Application number
EA202090225A
Other languages
Russian (ru)
Other versions
EA202090225A2 (en
Inventor
Мэттью Боттомлей
Энрико Малито
Мануэле Мартинелли
Мария Скарселли
Original Assignee
Глаксосмитклайн Байолоджикалс Са
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Глаксосмитклайн Байолоджикалс Са filed Critical Глаксосмитклайн Байолоджикалс Са
Publication of EA202090225A2 publication Critical patent/EA202090225A2/en
Publication of EA202090225A3 publication Critical patent/EA202090225A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/085—Picornaviridae, e.g. coxsackie virus, echovirus, enterovirus
    • C07K14/095—Rhinovirus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Авторы изобретения идентифицировали остатки в варианте 2 и варианте 3 менингококкового fHbp, которые могут быть модифицированы для увеличения его стабильности.The inventors have identified residues in variant 2 and variant 3 of meningococcal fHbp that can be modified to increase its stability.

EA202090225A 2014-07-17 2015-02-27 MODIFIED MENINGOCOCCAL FHBP POLYPEPTIDES EA202090225A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14177566 2014-07-17

Publications (2)

Publication Number Publication Date
EA202090225A2 EA202090225A2 (en) 2020-12-30
EA202090225A3 true EA202090225A3 (en) 2021-04-30

Family

ID=51178813

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202090225A EA202090225A3 (en) 2014-07-17 2015-02-27 MODIFIED MENINGOCOCCAL FHBP POLYPEPTIDES

Country Status (2)

Country Link
EA (1) EA202090225A3 (en)
PT (1) PT3110442T (en)

Also Published As

Publication number Publication date
PT3110442T (en) 2020-12-15
EA202090225A2 (en) 2020-12-30

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