EA202090128A3 - ANTIBODIES AGAINST ANTIGEN 2 BLOOD DENDRITIC CELLS AND THEIR APPLICATION - Google Patents

ANTIBODIES AGAINST ANTIGEN 2 BLOOD DENDRITIC CELLS AND THEIR APPLICATION

Info

Publication number
EA202090128A3
EA202090128A3 EA202090128A EA202090128A EA202090128A3 EA 202090128 A3 EA202090128 A3 EA 202090128A3 EA 202090128 A EA202090128 A EA 202090128A EA 202090128 A EA202090128 A EA 202090128A EA 202090128 A3 EA202090128 A3 EA 202090128A3
Authority
EA
Eurasian Patent Office
Prior art keywords
application
dendritic cells
antibodies against
against antigen
blood dendritic
Prior art date
Application number
EA202090128A
Other languages
Russian (ru)
Other versions
EA202090128A2 (en
Inventor
Джастин А. Каравелла
Эллен А. Гарбер
Даниа Мунир Рабах
Фредерик Р. Тэйлор
Original Assignee
Байоджен Ма Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Байоджен Ма Инк. filed Critical Байоджен Ма Инк.
Publication of EA202090128A2 publication Critical patent/EA202090128A2/en
Publication of EA202090128A3 publication Critical patent/EA202090128A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

В изобретении раскрыты антитела и фрагменты антител, которые связываются с BDCA2. Также описаны способы применения антител и фрагментов антител для индукции гибели плазмоцитоидных дендритных клеток, ингибирования продукции или секреции воспалительных цитокинов и хемокинов и для лечения или профилактики иммунологических заболеваний, таких как воспалительные и аутоиммунные состояния.The invention discloses antibodies and antibody fragments that bind to BDCA2. Also described are methods of using antibodies and antibody fragments to induce plasmacytoid dendritic cell death, inhibit the production or secretion of inflammatory cytokines and chemokines, and to treat or prevent immunological diseases such as inflammatory and autoimmune conditions.

EA202090128A 2013-02-11 2013-12-10 ANTIBODIES AGAINST ANTIGEN 2 BLOOD DENDRITIC CELLS AND THEIR APPLICATION EA202090128A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361763270P 2013-02-11 2013-02-11

Publications (2)

Publication Number Publication Date
EA202090128A2 EA202090128A2 (en) 2020-08-31
EA202090128A3 true EA202090128A3 (en) 2020-12-30

Family

ID=72235071

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202090128A EA202090128A3 (en) 2013-02-11 2013-12-10 ANTIBODIES AGAINST ANTIGEN 2 BLOOD DENDRITIC CELLS AND THEIR APPLICATION

Country Status (1)

Country Link
EA (1) EA202090128A3 (en)

Also Published As

Publication number Publication date
EA202090128A2 (en) 2020-08-31

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