EA202090066A1 - THERAPEUTIC FOR THE TREATMENT OF ASPIRATED PNEUMONIA, PULMONARY FORCING OR LUNG ABCESS - Google Patents
THERAPEUTIC FOR THE TREATMENT OF ASPIRATED PNEUMONIA, PULMONARY FORCING OR LUNG ABCESSInfo
- Publication number
- EA202090066A1 EA202090066A1 EA202090066A EA202090066A EA202090066A1 EA 202090066 A1 EA202090066 A1 EA 202090066A1 EA 202090066 A EA202090066 A EA 202090066A EA 202090066 A EA202090066 A EA 202090066A EA 202090066 A1 EA202090066 A1 EA 202090066A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- treatment
- pulmonary
- pneumonia
- aspirated
- forcing
- Prior art date
Links
- 206010035664 Pneumonia Diseases 0.000 title 1
- 210000004072 lung Anatomy 0.000 title 1
- 230000002685 pulmonary effect Effects 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 2
- ZFIOCUITTUUVPV-MEDUHNTESA-N 7-[(3s,4s)-3-[(cyclopropylamino)methyl]-4-fluoropyrrolidin-1-yl]-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-oxoquinoline-3-carboxylic acid Chemical compound C([C@@H]1[C@H](F)CN(C1)C1=C(C2=C(C(C(C(O)=O)=CN2CCF)=O)C=C1F)OC)NC1CC1 ZFIOCUITTUUVPV-MEDUHNTESA-N 0.000 abstract 1
- 208000032376 Lung infection Diseases 0.000 abstract 1
- 206010035669 Pneumonia aspiration Diseases 0.000 abstract 1
- 206010057190 Respiratory tract infections Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 201000009807 aspiration pneumonia Diseases 0.000 abstract 1
- 201000003453 lung abscess Diseases 0.000 abstract 1
- 208000020029 respiratory tract infectious disease Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Настоящее изобретение относится к безопасному и более эффективному терапевтическому средству для лечения инфекций дыхательных путей. Решение: терапевтическое средство для лечения аспирационной пневмонии, легочного нагноения или абсцесса легких, включающее в качестве активного ингредиента 7-[(3S,4S)-3-{(циклопропиламино)метил}-4-фторпирролидин-1-ил]-6-фтор-1-(2-фторэтил)-8-метокси-4-оксо-1,4-дигидрохинолин-3-карбоновую кислоту или ее фармацевтически приемлемую соль.The present invention relates to a safer and more effective therapeutic agent for the treatment of respiratory tract infections. Solution: A therapeutic agent for the treatment of aspiration pneumonia, pulmonary suppuration or lung abscess, containing as an active ingredient 7-[(3S,4S)-3-{(cyclopropylamino)methyl}-4-fluoropyrrolidin-1-yl]-6-fluoro -1-(2-fluoroethyl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2018068159 | 2018-03-30 | ||
PCT/JP2018/022846 WO2018230686A1 (en) | 2017-06-16 | 2018-06-15 | Therapeutic agent for aspiration pneumonia, lung suppuration, or lung abscess |
Publications (1)
Publication Number | Publication Date |
---|---|
EA202090066A1 true EA202090066A1 (en) | 2020-04-15 |
Family
ID=64660738
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA202090066A EA202090066A1 (en) | 2018-03-30 | 2018-06-15 | THERAPEUTIC FOR THE TREATMENT OF ASPIRATED PNEUMONIA, PULMONARY FORCING OR LUNG ABCESS |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN116549446A (en) |
EA (1) | EA202090066A1 (en) |
WO (1) | WO2018230686A1 (en) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1666477E (en) | 2003-09-10 | 2013-08-28 | Kyorin Seiyaku Kk | 7-(4-substituted 3- cyclopropylaminomethyl-1- pyrrolidinyl) q uinolonecarboxylic acid derivative |
SA112330992B1 (en) | 2011-11-10 | 2015-09-13 | كيورين فارماسوتيكال كو.، ليمتد | Crystalline form of the 7-{(3S,4S)-3 [(cyclopropylamino)methyl]-4- fluoropyrrolidine-1-YL}-6-fluoro-1-(2-fluoroethyl)-8-methoxy-4-OXO- 1,4-dihydroquinoline-3-carboxylic acid |
US20180042918A1 (en) * | 2015-03-13 | 2018-02-15 | Kyorin Pharmaceutical Co., Ltd. | Respiratory infection treating agent |
CA2987879A1 (en) | 2015-06-02 | 2016-12-08 | Kyorin Pharmaceutical Co., Ltd. | Aqueous drug |
-
2018
- 2018-06-15 WO PCT/JP2018/022846 patent/WO2018230686A1/en active Application Filing
- 2018-06-15 CN CN202310755318.XA patent/CN116549446A/en active Pending
- 2018-06-15 EA EA202090066A patent/EA202090066A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN116549446A (en) | 2023-08-08 |
WO2018230686A1 (en) | 2018-12-20 |
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