EA202090016A3 - STABILIZED COMPOSITIONS CONTAINING ANTIBODIES TO THE INTERLEUKIN-4 (IL-4R) RECEPTOR - Google Patents

STABILIZED COMPOSITIONS CONTAINING ANTIBODIES TO THE INTERLEUKIN-4 (IL-4R) RECEPTOR

Info

Publication number
EA202090016A3
EA202090016A3 EA202090016A EA202090016A EA202090016A3 EA 202090016 A3 EA202090016 A3 EA 202090016A3 EA 202090016 A EA202090016 A EA 202090016A EA 202090016 A EA202090016 A EA 202090016A EA 202090016 A3 EA202090016 A3 EA 202090016A3
Authority
EA
Eurasian Patent Office
Prior art keywords
compositions containing
interleukin
receptor
containing antibodies
stabilized compositions
Prior art date
Application number
EA202090016A
Other languages
Russian (ru)
Other versions
EA202090016A2 (en
Inventor
Дэниел Б. Дикс
Сяолинь Тан
Original Assignee
Ридженерон Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ридженерон Фармасьютикалз, Инк. filed Critical Ридженерон Фармасьютикалз, Инк.
Priority claimed from US13/253,103 external-priority patent/US8945559B2/en
Publication of EA202090016A2 publication Critical patent/EA202090016A2/en
Publication of EA202090016A3 publication Critical patent/EA202090016A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

Настоящее изобретение относится к дозированным формам жидких фармацевтических композиций, содержащих человеческие антитела, которые специфически связываются с альфа-рецептором человеческого интерлейкина-4 (hIL-4R). Фармацевтические композиции по настоящему изобретению проявляют существенную степень стабильности антител после хранения в течение нескольких месяцев.The present invention relates to dosage forms of liquid pharmaceutical compositions containing human antibodies that specifically bind to the alpha receptor of human interleukin-4 (hIL-4R). The pharmaceutical compositions of the present invention exhibit a significant degree of antibody stability after storage for several months.

EA202090016A 2011-10-05 2011-10-05 STABILIZED COMPOSITIONS CONTAINING ANTIBODIES TO THE INTERLEUKIN-4 (IL-4R) RECEPTOR EA202090016A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13/253,103 US8945559B2 (en) 2010-10-06 2011-10-05 Stabilized formulations containing anti-interleukin-4 receptor (IL-4R) antibodies

Publications (2)

Publication Number Publication Date
EA202090016A2 EA202090016A2 (en) 2020-04-30
EA202090016A3 true EA202090016A3 (en) 2020-07-31

Family

ID=70483869

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202090016A EA202090016A3 (en) 2011-10-05 2011-10-05 STABILIZED COMPOSITIONS CONTAINING ANTIBODIES TO THE INTERLEUKIN-4 (IL-4R) RECEPTOR

Country Status (1)

Country Link
EA (1) EA202090016A3 (en)

Also Published As

Publication number Publication date
EA202090016A2 (en) 2020-04-30

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