EA201992245A1 - ANALYTICAL AND THERAPEUTIC METHODS AND COMPOSITIONS AND THEIR APPLICATION - Google Patents

ANALYTICAL AND THERAPEUTIC METHODS AND COMPOSITIONS AND THEIR APPLICATION

Info

Publication number
EA201992245A1
EA201992245A1 EA201992245A EA201992245A EA201992245A1 EA 201992245 A1 EA201992245 A1 EA 201992245A1 EA 201992245 A EA201992245 A EA 201992245A EA 201992245 A EA201992245 A EA 201992245A EA 201992245 A1 EA201992245 A1 EA 201992245A1
Authority
EA
Eurasian Patent Office
Prior art keywords
compositions
methods
polypeptides
analytical
application
Prior art date
Application number
EA201992245A
Other languages
Russian (ru)
Inventor
Николь Дж Морленд
Пол Гэри Янг
Томас Профт
Original Assignee
Окленд Юнисервисиз Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Окленд Юнисервисиз Лимитед filed Critical Окленд Юнисервисиз Лимитед
Priority claimed from PCT/NZ2018/050057 external-priority patent/WO2018199775A1/en
Publication of EA201992245A1 publication Critical patent/EA201992245A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56944—Streptococcus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/315—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Streptococcus (G), e.g. Enterococci
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy

Abstract

Изобретение в целом относится к композициям и способам лечения, обнаружения и оказания помощи при диагностике инфекции Streptococcus pyogenes, ревматизма или постстрептококкового гломерулонефрита (PSGN), а также к композициям и способам оценки склонности к развитию ревматизма или PSGN у субъектов, нуждающихся в этом. Также предложены рекомбинантные полипептиды, включая рекомбинантные полипептиды SpnA Streptococcus pyogenes, и комбинации, содержащие такие полипептиды, для применения в указанных способах.The invention generally relates to compositions and methods for treating, detecting and assisting in the diagnosis of Streptococcus pyogenes infection, rheumatism or post-streptococcal glomerulonephritis (PSGN), as well as compositions and methods for assessing the tendency to develop rheumatism or PSGN in subjects in need thereof. Also proposed are recombinant polypeptides, including recombinant SpnA Streptococcus pyogenes polypeptides, and combinations containing such polypeptides for use in these methods.

EA201992245A 2017-10-16 2018-04-26 ANALYTICAL AND THERAPEUTIC METHODS AND COMPOSITIONS AND THEIR APPLICATION EA201992245A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ73644817 2017-10-16
PCT/NZ2018/050057 WO2018199775A1 (en) 2017-04-26 2018-04-26 Analytical and therapeutic methods and compositions, and uses thereof

Publications (1)

Publication Number Publication Date
EA201992245A1 true EA201992245A1 (en) 2020-03-10

Family

ID=69942828

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201992245A EA201992245A1 (en) 2017-10-16 2018-04-26 ANALYTICAL AND THERAPEUTIC METHODS AND COMPOSITIONS AND THEIR APPLICATION

Country Status (1)

Country Link
EA (1) EA201992245A1 (en)

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