EA201992174A1 - OPTIONS OF IMMUNOMODULATING PROTEINS CD80 AND THEIR APPLICATION - Google Patents

OPTIONS OF IMMUNOMODULATING PROTEINS CD80 AND THEIR APPLICATION

Info

Publication number
EA201992174A1
EA201992174A1 EA201992174A EA201992174A EA201992174A1 EA 201992174 A1 EA201992174 A1 EA 201992174A1 EA 201992174 A EA201992174 A EA 201992174A EA 201992174 A EA201992174 A EA 201992174A EA 201992174 A1 EA201992174 A1 EA 201992174A1
Authority
EA
Eurasian Patent Office
Prior art keywords
proteins
options
application
immunomodulating proteins
polypeptides
Prior art date
Application number
EA201992174A
Other languages
Russian (ru)
Inventor
Райан Свонсон
Майкл Корнакер
Марк Ф. Маурер
Дэн Ардурел
Дэниэл Уилльям Демонт
Джозеф Л. Куийпер
Original Assignee
Элпайн Иммьюн Сайенсиз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Элпайн Иммьюн Сайенсиз, Инк. filed Critical Элпайн Иммьюн Сайенсиз, Инк.
Priority claimed from PCT/US2018/022270 external-priority patent/WO2018170026A2/en
Publication of EA201992174A1 publication Critical patent/EA201992174A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70532—B7 molecules, e.g. CD80, CD86

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Настоящее изобретение относится к вариантам полипептидов CD80, иммуномодулирующим белкам, содержащим варианты полипептидов CD80, и нуклеиновым кислотам, кодирующим такие белки. Иммуномодулирующие белки обладают терапевтической применимостью в отношении различных иммунологических и онкологических заболеваний. Настоящее изобретение относится к композициям и способам для получения и применения таких белков.The present invention relates to variants of CD80 polypeptides, immunomodulatory proteins containing variants of CD80 polypeptides, and nucleic acids encoding such proteins. Immunomodulating proteins have therapeutic utility in relation to various immunological and oncological diseases. The present invention relates to compositions and methods for the preparation and use of such proteins.

EA201992174A 2017-11-06 2018-03-13 OPTIONS OF IMMUNOMODULATING PROTEINS CD80 AND THEIR APPLICATION EA201992174A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762582266P 2017-11-06 2017-11-06
PCT/US2018/022270 WO2018170026A2 (en) 2017-03-16 2018-03-13 Cd80 variant immunomodulatory proteins and uses thereof

Publications (1)

Publication Number Publication Date
EA201992174A1 true EA201992174A1 (en) 2020-01-17

Family

ID=69374495

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201992174A EA201992174A1 (en) 2017-11-06 2018-03-13 OPTIONS OF IMMUNOMODULATING PROTEINS CD80 AND THEIR APPLICATION

Country Status (1)

Country Link
EA (1) EA201992174A1 (en)

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