EA201991531A1 - METHODS OF TREATMENT OF LINACLOTIDE COMPOSITIONS WITH DELAYED DELIVERY - Google Patents

METHODS OF TREATMENT OF LINACLOTIDE COMPOSITIONS WITH DELAYED DELIVERY

Info

Publication number
EA201991531A1
EA201991531A1 EA201991531A EA201991531A EA201991531A1 EA 201991531 A1 EA201991531 A1 EA 201991531A1 EA 201991531 A EA201991531 A EA 201991531A EA 201991531 A EA201991531 A EA 201991531A EA 201991531 A1 EA201991531 A1 EA 201991531A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methods
treatment
delayed delivery
gastrointestinal tract
linaclotide
Prior art date
Application number
EA201991531A
Other languages
Russian (ru)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of EA201991531A1 publication Critical patent/EA201991531A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives

Abstract

Изобретение относится к способам лечения пациента с нарушением, таким как нарушение ЖКТ, или симптомами, ассоциированными с нарушением ЖКТ или не в ЖКТ, посредством введения терапевтически эффективного количества фармацевтической композиции с отсроченным высвобождением, содержащей линаклотид.The invention relates to methods of treating a patient with a disorder, such as a gastrointestinal tract disorder, or symptoms associated with a gastrointestinal tract disorder or not in the gastrointestinal tract, by administering a therapeutically effective amount of a delayed release pharmaceutical composition containing a linaclotide.

EA201991531A 2016-12-21 2017-12-21 METHODS OF TREATMENT OF LINACLOTIDE COMPOSITIONS WITH DELAYED DELIVERY EA201991531A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662437566P 2016-12-21 2016-12-21
PCT/US2017/067814 WO2018119191A1 (en) 2016-12-21 2017-12-21 Methods of treating irritable bowel syndrome with modified or delayed release formulations of linaclotide

Publications (1)

Publication Number Publication Date
EA201991531A1 true EA201991531A1 (en) 2019-11-29

Family

ID=61022424

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201991531A EA201991531A1 (en) 2016-12-21 2017-12-21 METHODS OF TREATMENT OF LINACLOTIDE COMPOSITIONS WITH DELAYED DELIVERY

Country Status (10)

Country Link
EP (1) EP3558337A1 (en)
JP (2) JP2020512292A (en)
CN (1) CN110475564A (en)
AU (1) AU2017379082A1 (en)
BR (1) BR112019012689A2 (en)
CA (1) CA3048195A1 (en)
EA (1) EA201991531A1 (en)
MA (1) MA47112A (en)
MX (1) MX2019007574A (en)
WO (1) WO2018119191A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3140528A1 (en) * 2019-06-10 2020-12-17 Wilmin Bartolini Treatment of abdominal pain associated with diarrhea-predominant irritable bowel syndrome
WO2023097309A1 (en) * 2021-11-29 2023-06-01 Ironwood Pharmaceuticals, Inc. Pharmaceutical compositions for the treatment of visceral pain
WO2023196821A2 (en) * 2022-04-04 2023-10-12 Thomas Jefferson University Targeting neuropod cell gucy2c to control visceral pain and appetite

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7304036B2 (en) 2003-01-28 2007-12-04 Microbia, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US7371727B2 (en) 2003-01-28 2008-05-13 Microbia, Inc. Methods and compositions for the treatment of gastrointestinal disorders
EP3701962A1 (en) 2008-08-15 2020-09-02 Ironwood Pharmaceuticals, Inc. Stable solid formulation of a gc-c receptor agonist polypeptide suitable for oral administration
EP2464373A1 (en) * 2009-08-13 2012-06-20 Ironwood Pharmaceuticals, Inc. Method for modulating the pharmacodynamic effect of orally administered guanylate cyclase receptor agonists
WO2011103311A2 (en) 2010-02-17 2011-08-25 Ironwood Pharmaceuticals, Inc Treatments for gastrointestinal disorders
LT2603232T (en) * 2010-08-11 2020-01-27 Ironwood Pharmaceuticals, Inc. Stable formulations of linaclotide
WO2013025969A1 (en) 2011-08-17 2013-02-21 Ironwood Pharmaceuticals, Inc. Treatments for gastrointestinal disorders
CN108057028A (en) * 2013-01-15 2018-05-22 铁木医药有限公司 The Entogastric lingering peroral dosage form of the enteric coating of tablet form and its application and pharmaceutical composition
UA119335C2 (en) * 2013-12-11 2019-06-10 Айронвуд Фармасьютикалз, Інк. Delayed release compositions of linaclotide
ES2868873T3 (en) * 2015-06-05 2021-10-22 Ironwood Pharmaceuticals Inc Modified or targeted release formulations of linaclotide

Also Published As

Publication number Publication date
BR112019012689A2 (en) 2019-11-19
MA47112A (en) 2019-10-30
AU2017379082A1 (en) 2019-07-04
JP2022093472A (en) 2022-06-23
CA3048195A1 (en) 2018-06-28
WO2018119191A9 (en) 2019-08-29
WO2018119191A1 (en) 2018-06-28
JP2020512292A (en) 2020-04-23
MX2019007574A (en) 2019-09-04
CN110475564A (en) 2019-11-19
EP3558337A1 (en) 2019-10-30

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