EA201991290A1 - VISUALIZATION OF TUMOR AND IMMUNE CELLS BASED ON PD-L1 EXPRESSION - Google Patents

VISUALIZATION OF TUMOR AND IMMUNE CELLS BASED ON PD-L1 EXPRESSION

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Publication number
EA201991290A1
EA201991290A1 EA201991290A EA201991290A EA201991290A1 EA 201991290 A1 EA201991290 A1 EA 201991290A1 EA 201991290 A EA201991290 A EA 201991290A EA 201991290 A EA201991290 A EA 201991290A EA 201991290 A1 EA201991290 A1 EA 201991290A1
Authority
EA
Eurasian Patent Office
Prior art keywords
visualization
tumor
expression
immune cells
cells based
Prior art date
Application number
EA201991290A
Other languages
Russian (ru)
Inventor
Сридхар Ниммагадда
Мартин Г. Помпер
Самит Чаттерджи
Войцех Г. Лесняк
Дхирадж Кумар
Original Assignee
Дзе Джонс Хопкинс Юниверсити
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дзе Джонс Хопкинс Юниверсити filed Critical Дзе Джонс Хопкинс Юниверсити
Priority claimed from PCT/US2017/068025 external-priority patent/WO2018119313A1/en
Publication of EA201991290A1 publication Critical patent/EA201991290A1/en

Links

Abstract

В качестве раскрываемого объекта изобретения предлагаются композиции, наборы и способы, включающие визуализирующие средства, которые позволяют осуществлять детекцию лиганда 1 белка программируемой смерти клеток (PD-L1). Раскрытые в настоящем изобретении визуализирующие средства могут применяться для детекции заболеваний и расстройств у субъекта, таких как рак, инфекция и воспаление.As a disclosed subject matter of the invention, compositions, kits and methods are provided, including imaging agents that allow the detection of ligand 1 of programmed cell death protein (PD-L1). The imaging agents disclosed in the present invention can be used to detect diseases and disorders in a subject, such as cancer, infection, and inflammation.

EA201991290A 2017-06-14 2017-12-21 VISUALIZATION OF TUMOR AND IMMUNE CELLS BASED ON PD-L1 EXPRESSION EA201991290A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762519534P 2017-06-14 2017-06-14
PCT/US2017/068025 WO2018119313A1 (en) 2016-12-23 2017-12-21 Tumor and immune cell imaging based on pd-l1 expression

Publications (1)

Publication Number Publication Date
EA201991290A1 true EA201991290A1 (en) 2019-12-30

Family

ID=69061900

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201991290A EA201991290A1 (en) 2017-06-14 2017-12-21 VISUALIZATION OF TUMOR AND IMMUNE CELLS BASED ON PD-L1 EXPRESSION

Country Status (1)

Country Link
EA (1) EA201991290A1 (en)

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