EA201990774A1 - Способ независимой от источника углерода селективной экспрессии белок-кодирующих последовательностей в клетке мицелиального гриба - Google Patents

Способ независимой от источника углерода селективной экспрессии белок-кодирующих последовательностей в клетке мицелиального гриба

Info

Publication number
EA201990774A1
EA201990774A1 EA201990774A EA201990774A EA201990774A1 EA 201990774 A1 EA201990774 A1 EA 201990774A1 EA 201990774 A EA201990774 A EA 201990774A EA 201990774 A EA201990774 A EA 201990774A EA 201990774 A1 EA201990774 A1 EA 201990774A1
Authority
EA
Eurasian Patent Office
Prior art keywords
selective
protein
cell
micellous
mushroom
Prior art date
Application number
EA201990774A
Other languages
English (en)
Inventor
Кристиан Гамауф
Георг Ширмахер
Бернхард Зайбот
Кристиан П. Кубицек
Роберт Бишоф
Original Assignee
Клариант Интернэшнл Лтд
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Клариант Интернэшнл Лтд filed Critical Клариант Интернэшнл Лтд
Publication of EA201990774A1 publication Critical patent/EA201990774A1/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Изобретение относится к способу независимой от источника углерода селективной экспрессии белок-кодирующих последовательностей в клетке мицелиального гриба, а также к применению такого промотора для независимой от источника углерода селективной экспрессии белок-кодирующих последовательностей в клетке мицелиального гриба.
EA201990774A 2016-09-20 2017-09-19 Способ независимой от источника углерода селективной экспрессии белок-кодирующих последовательностей в клетке мицелиального гриба EA201990774A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16189598.2A EP3296401B1 (en) 2016-09-20 2016-09-20 Method for selective carbon source-independent expression of protein-encoding sequences in a filamentous fungus cell
PCT/EP2017/073681 WO2018054924A1 (en) 2016-09-20 2017-09-19 Method for selective carbon source-independent expression of protein-encoding sequences in a filamentous fungus cell

Publications (1)

Publication Number Publication Date
EA201990774A1 true EA201990774A1 (ru) 2019-08-30

Family

ID=56990248

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201990774A EA201990774A1 (ru) 2016-09-20 2017-09-19 Способ независимой от источника углерода селективной экспрессии белок-кодирующих последовательностей в клетке мицелиального гриба

Country Status (13)

Country Link
EP (1) EP3296401B1 (ru)
CN (1) CN109715809B (ru)
AU (1) AU2017329752B2 (ru)
CA (1) CA3035981C (ru)
DK (1) DK3296401T3 (ru)
EA (1) EA201990774A1 (ru)
ES (1) ES2784318T3 (ru)
HR (1) HRP20200622T1 (ru)
HU (1) HUE049275T2 (ru)
PL (1) PL3296401T3 (ru)
RS (1) RS60238B1 (ru)
SI (1) SI3296401T1 (ru)
WO (1) WO2018054924A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3296401B1 (en) * 2016-09-20 2020-02-19 Clariant International Ltd Method for selective carbon source-independent expression of protein-encoding sequences in a filamentous fungus cell

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2287989T3 (es) * 1997-12-22 2007-12-16 Dsm Ip Assets B.V. Clonacion de expresion en hongos filamentosos.
EP1059354A2 (en) * 1999-06-10 2000-12-13 Ceres Incorporated Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
CN105420267A (zh) * 2010-11-30 2016-03-23 诺维信股份有限公司 用于在真菌细胞中表达基因的启动子
DK2652138T3 (en) * 2010-12-16 2018-01-22 Novozymes Inc Promoters for expression of genes in a fungal cell
CN102311951B (zh) * 2011-07-13 2013-03-20 深圳大学 里氏木霉组成型表达盒、表达载体、重组菌株及其应用
CN102876706B (zh) * 2012-08-01 2014-03-26 中国科学院微生物研究所 高通量筛选高效表达外源蛋白的重组里氏木霉的方法
CN103114089B (zh) * 2012-12-05 2014-06-25 中国科学院天津工业生物技术研究所 源于里氏木霉的强启动子及其表达载体和应用
CN104975039B (zh) * 2015-06-24 2018-05-11 方诩 一种重组质粒及其在降解纤维素原料中的应用
CN105602919A (zh) * 2015-12-08 2016-05-25 中国农业科学院饲料研究所 一种利用rna干扰技术提高里氏木霉生产纤维素酶的方法
EP3296401B1 (en) * 2016-09-20 2020-02-19 Clariant International Ltd Method for selective carbon source-independent expression of protein-encoding sequences in a filamentous fungus cell

Also Published As

Publication number Publication date
CA3035981A1 (en) 2018-03-29
WO2018054924A1 (en) 2018-03-29
AU2017329752B2 (en) 2020-12-24
HRP20200622T1 (hr) 2020-07-10
SI3296401T1 (sl) 2020-07-31
CN109715809A (zh) 2019-05-03
AU2017329752A1 (en) 2019-03-21
HUE049275T2 (hu) 2020-09-28
CN109715809B (zh) 2023-04-14
EP3296401A1 (en) 2018-03-21
PL3296401T3 (pl) 2020-07-27
ES2784318T3 (es) 2020-09-24
RS60238B1 (sr) 2020-06-30
DK3296401T3 (da) 2020-05-04
EP3296401B1 (en) 2020-02-19
CA3035981C (en) 2021-08-24

Similar Documents

Publication Publication Date Title
CY1124921T1 (el) Μεθοδοι για την εκχυλιση και τον καθαρισμο μη μετουσιωμενων πρωτεϊνων
CO2019013609A2 (es) Vectores de neoantígeno de alfavirus
MX2017003847A (es) Proteinas biespecificas activables por proteasas.
MX2023011785A (es) Metodos y composiciones para produccion de proteina de clara de huevo.
CO2018005876A2 (es) Inmunoglobulinas conjugadas con lisina c-terminal
MX2018010842A (es) Expresion mediada por el virus adeno-asociado (aav) usando un promotor y pontenciador sintetico.
EP4324473A3 (en) Multiparametric nucleic acid optimization
BR112016016916A2 (pt) método de tratamento de angiodema hereditário (hae)
EA201591294A1 (ru) Рекомбинантный микроорганизм для применения в способе с повышенным выходом продукта
ES2721309T3 (es) Composición para preparar tagatosa y método para preparar tagatosa a partir de fructosa
BR112017016897A2 (pt) cepas fúngicas e métodos de uso
UY35444A (es) Anticuerpos anti-tnf alfa mutados y métodos para su utilización
PH12016501094A1 (en) Recombinant microorganism for improved production of fine chemicals
PH12017501678A1 (en) Recombinant microorganism for improved production of finie chemicals
MX2016004802A (es) Anticuerpos anti-r-espondina (anti-rspo) y metodos de uso.
MX2015014424A (es) Construcciones de proteinas mitocondriales y sus usos.
CU20160008A7 (es) Métodos para controlar los niveles de fucosilacion en proteinas
EA201400940A1 (ru) Способ получения медетомидина
BR112018009097A2 (pt) spodoptera frugiperda resistente a vip3a
TR201903795T4 (tr) Ngs si̇stemleri̇ kontrolü ve bunu kapsayan yöntemler
MY184391A (en) Microorganism having improved intracellular energy level and method for producing l-amino acid using same
EA201990774A1 (ru) Способ независимой от источника углерода селективной экспрессии белок-кодирующих последовательностей в клетке мицелиального гриба
EA201790725A1 (ru) Основанные на близости расположения способы выбора партнеров для связывания
EA201790360A1 (ru) Получение полностью процессированного и функционального фактора x в фурин-секретирующей системе экспрессии млекопитающего
CO2017012397A2 (es) Fragmento de anticuerpo fab anti-ngf humano