EA201990771A1 - DOPAMIN-β-HYDROXYLASE INHIBITORS - Google Patents
DOPAMIN-β-HYDROXYLASE INHIBITORSInfo
- Publication number
- EA201990771A1 EA201990771A1 EA201990771A EA201990771A EA201990771A1 EA 201990771 A1 EA201990771 A1 EA 201990771A1 EA 201990771 A EA201990771 A EA 201990771A EA 201990771 A EA201990771 A EA 201990771A EA 201990771 A1 EA201990771 A1 EA 201990771A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- compounds
- solvates
- salts
- dopamin
- hydroxylase inhibitors
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Настоящее изобретение относится к (a) соединениям формулы (Ia) (где фрагменты R, R, R, R, а также n и A соответствуют определениям, приведенным в данном документе) и их фармацевтически приемлемым солям или сольватам, которые могут применяться в качестве ингибиторов дофамин-β-гидроксилазы; (b) фармацевтическим композициям, содержащим такие соединения, соли или сольваты; (c) к применению таких соединений, солей или сольватов в терапии; (d) к терапевтическим способам лечения с использованием таких соединений, солей или сольватов и (e) к способам и промежуточным соединениям, подходящим для синтеза таких соединений.The present invention relates to (a) compounds of formula (Ia) (where the fragments R, R, R, R, as well as n and A are as defined herein) and their pharmaceutically acceptable salts or solvates thereof which may be used as inhibitors dopamine β-hydroxylase; (b) pharmaceutical compositions containing such compounds, salts or solvates; (c) the use of such compounds, salts or solvates in therapy; (d) to therapeutic treatments using such compounds, salts or solvates; and (e) to methods and intermediates suitable for synthesizing such compounds.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1713779.5A GB201713779D0 (en) | 2017-08-29 | 2017-08-29 | Blood-brain barrier-penetrant dopamine B-hydroxylase inhibitors |
| PCT/PT2017/050023 WO2018056855A1 (en) | 2016-09-23 | 2017-09-22 | Dopamine-b-hydroxylase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201990771A1 true EA201990771A1 (en) | 2019-08-30 |
Family
ID=60037079
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201990771A EA201990771A1 (en) | 2017-08-29 | 2017-09-22 | DOPAMIN-β-HYDROXYLASE INHIBITORS |
| EA201990763A EA201990763A1 (en) | 2017-08-29 | 2017-09-22 | DOPAMINE-B-HYDROXYLASE INHIBITORS penetrating through the blood-brain barrier |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201990763A EA201990763A1 (en) | 2017-08-29 | 2017-09-22 | DOPAMINE-B-HYDROXYLASE INHIBITORS penetrating through the blood-brain barrier |
Country Status (2)
| Country | Link |
|---|---|
| EA (2) | EA201990771A1 (en) |
| GB (1) | GB201713779D0 (en) |
-
2017
- 2017-08-29 GB GBGB1713779.5A patent/GB201713779D0/en not_active Ceased
- 2017-09-22 EA EA201990771A patent/EA201990771A1/en unknown
- 2017-09-22 EA EA201990763A patent/EA201990763A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA201990763A1 (en) | 2019-08-30 |
| GB201713779D0 (en) | 2017-10-11 |
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