EA201990426A1 - Spiro-Lactam Modulators of the NMDA Receptor and Their Application - Google Patents

Spiro-Lactam Modulators of the NMDA Receptor and Their Application

Info

Publication number
EA201990426A1
EA201990426A1 EA201990426A EA201990426A EA201990426A1 EA 201990426 A1 EA201990426 A1 EA 201990426A1 EA 201990426 A EA201990426 A EA 201990426A EA 201990426 A EA201990426 A EA 201990426A EA 201990426 A1 EA201990426 A1 EA 201990426A1
Authority
EA
Eurasian Patent Office
Prior art keywords
nmda receptor
lactam
spiro
modulators
application
Prior art date
Application number
EA201990426A
Other languages
Russian (ru)
Inventor
М. Амин Кхан
Original Assignee
Аптиникс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Аптиникс Инк. filed Critical Аптиникс Инк.
Priority claimed from PCT/US2017/044813 external-priority patent/WO2018026763A1/en
Publication of EA201990426A1 publication Critical patent/EA201990426A1/en

Links

Abstract

Раскрыты соединения, обладающие повышенной эффективностью при модулировании активности рецептора NMDA. Такие соединения могут применяться при лечении состояний, таких как депрессивный синдром и родственные расстройства. Также раскрыты перорально доступные лекарственные формы и другие фармацевтически приемлемые формы доставки соединений, включая лекарственные формы для внутривенного введения.Disclosed are compounds having enhanced efficacy in modulating NMDA receptor activity. Such compounds can be used in the treatment of conditions such as depressive syndrome and related disorders. Orally available dosage forms and other pharmaceutically acceptable forms of delivery of the compounds, including intravenous dosage forms, are also disclosed.

EA201990426A 2017-06-22 2017-08-01 Spiro-Lactam Modulators of the NMDA Receptor and Their Application EA201990426A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762523413P 2017-06-22 2017-06-22
PCT/US2017/044813 WO2018026763A1 (en) 2016-08-01 2017-08-01 Spiro-lactam nmda receptor modulators and uses thereof

Publications (1)

Publication Number Publication Date
EA201990426A1 true EA201990426A1 (en) 2019-08-30

Family

ID=67734911

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201990426A EA201990426A1 (en) 2017-06-22 2017-08-01 Spiro-Lactam Modulators of the NMDA Receptor and Their Application

Country Status (1)

Country Link
EA (1) EA201990426A1 (en)

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