EA201892523A1 - MONOCLONAL DNA ANTIBODIES AIMED AT THE FLU VIRUS - Google Patents

MONOCLONAL DNA ANTIBODIES AIMED AT THE FLU VIRUS

Info

Publication number
EA201892523A1
EA201892523A1 EA201892523A EA201892523A EA201892523A1 EA 201892523 A1 EA201892523 A1 EA 201892523A1 EA 201892523 A EA201892523 A EA 201892523A EA 201892523 A EA201892523 A EA 201892523A EA 201892523 A1 EA201892523 A1 EA 201892523A1
Authority
EA
Eurasian Patent Office
Prior art keywords
flu virus
dna antibodies
antibodies aimed
monoclonal dna
monoclonal
Prior art date
Application number
EA201892523A
Other languages
Russian (ru)
Inventor
Дэвид Уэйнер
Сара Эллиотт
Ами Пател
Цзянь Янь
Original Assignee
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания
Дзе Уистар Инститьют Оф Энэтоми Энд Байолоджи
Иновио Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания, Дзе Уистар Инститьют Оф Энэтоми Энд Байолоджи, Иновио Фармасьютикалз, Инк. filed Critical Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания
Priority claimed from PCT/US2017/031213 external-priority patent/WO2017192946A1/en
Publication of EA201892523A1 publication Critical patent/EA201892523A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)

Abstract

В настоящем описании раскрыта композиция, включающая в себя рекомбинантную последовательность нуклеиновой кислоты, которая кодирует синтетическое антитело к гемагглютинину вируса гриппа. В настоящем описании также раскрыт способ предотвращения и/или лечения у субъекта гриппа с использованием указанной композиции и способ создания.In the present description disclosed is a composition comprising a recombinant nucleic acid sequence that encodes a synthetic antibody to the hemagglutinin of the influenza virus. The present disclosure also discloses a method of preventing and / or treating a subject of influenza using said composition and a method of creating.

EA201892523A 2016-08-17 2017-05-05 MONOCLONAL DNA ANTIBODIES AIMED AT THE FLU VIRUS EA201892523A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662376162P 2016-08-17 2016-08-17
PCT/US2017/031213 WO2017192946A1 (en) 2016-05-05 2017-05-05 Dna monoclonal antibodies targeting influenza virus

Publications (1)

Publication Number Publication Date
EA201892523A1 true EA201892523A1 (en) 2019-04-30

Family

ID=66436964

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201892523A EA201892523A1 (en) 2016-08-17 2017-05-05 MONOCLONAL DNA ANTIBODIES AIMED AT THE FLU VIRUS

Country Status (1)

Country Link
EA (1) EA201892523A1 (en)

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