EA201800348A1 - SUBSTITUTED 3-AZABICYCLO [3.1.0] Hexanes as ketohexinase inhibitors - Google Patents

SUBSTITUTED 3-AZABICYCLO [3.1.0] Hexanes as ketohexinase inhibitors

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Publication number
EA201800348A1
EA201800348A1 EA201800348A EA201800348A EA201800348A1 EA 201800348 A1 EA201800348 A1 EA 201800348A1 EA 201800348 A EA201800348 A EA 201800348A EA 201800348 A EA201800348 A EA 201800348A EA 201800348 A1 EA201800348 A1 EA 201800348A1
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EA
Eurasian Patent Office
Prior art keywords
azabicyclo
hexanes
substituted
inhibitors
ketohexinase
Prior art date
Application number
EA201800348A
Other languages
Russian (ru)
Other versions
EA035363B1 (en
Inventor
Мэттью Даулинг
Дилини Фернандо
Кентаро Футатсуги
Ким Хуард
Томас Виктор Маги
Брайан Рэймер
Андре Шавня
Аарон Смит
Бенджамин Тума
Энди Цай
Мэйхуа Ту
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Priority claimed from PCT/IB2016/057728 external-priority patent/WO2017115205A1/en
Publication of EA201800348A1 publication Critical patent/EA201800348A1/en
Publication of EA035363B1 publication Critical patent/EA035363B1/en

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Abstract

Предусмотренными в данном документе являются замещенные 3-азабицикло[3.1.0]гексаны в качестве ингибиторов кетогексокиназы, способы получения указанных соединений и способы, включающие введение указанных соединений млекопитающему, который в этом нуждается.Included in this document are substituted 3-azabicyclo [3.1.0] hexanes as ketohexokinase inhibitors, methods for producing these compounds, and methods including administering these compounds to a mammal in need.

EA201800348A 2016-11-17 2016-12-16 Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors EA035363B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662423549P 2016-11-17 2016-11-17
PCT/IB2016/057728 WO2017115205A1 (en) 2015-12-29 2016-12-16 Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors

Publications (2)

Publication Number Publication Date
EA201800348A1 true EA201800348A1 (en) 2019-03-29
EA035363B1 EA035363B1 (en) 2020-06-02

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Application Number Title Priority Date Filing Date
EA201800348A EA035363B1 (en) 2016-11-17 2016-12-16 Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors

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EA (1) EA035363B1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009049165A1 (en) * 2007-10-11 2009-04-16 Smithkline Beecham Corporation Novel seh inhibitors and their use
JP2013533289A (en) * 2010-08-06 2013-08-22 ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド，ア ボディー コーポレイト Methods and compositions for inhibiting fructokinase

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