EA201790832A1 - Ингалируемый состав - Google Patents

Ингалируемый состав

Info

Publication number
EA201790832A1
EA201790832A1 EA201790832A EA201790832A EA201790832A1 EA 201790832 A1 EA201790832 A1 EA 201790832A1 EA 201790832 A EA201790832 A EA 201790832A EA 201790832 A EA201790832 A EA 201790832A EA 201790832 A1 EA201790832 A1 EA 201790832A1
Authority
EA
Eurasian Patent Office
Prior art keywords
inhalable composition
active pharmaceutical
pharmaceutical ingredient
propellant
evaporating
Prior art date
Application number
EA201790832A
Other languages
English (en)
Inventor
Мукул Далви
Жаклин Маккейб
Original Assignee
Тева Брэндид Фармасьютикал Продактс Ар Энд Ди, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Тева Брэндид Фармасьютикал Продактс Ар Энд Ди, Инк. filed Critical Тева Брэндид Фармасьютикал Продактс Ар Энд Ди, Инк.
Publication of EA201790832A1 publication Critical patent/EA201790832A1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • A61K9/124Aerosols; Foams characterised by the propellant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Данное изобретение предоставляет способ приготовления ингалируемого активного фармацевтического ингредиента, включающий стадии нагревания суспензии активного фармацевтического ингредиента в сжиженном пропелленте в сосуде, выпаривания пропеллента и сбора полученного порошка.
EA201790832A 2014-10-16 2015-10-16 Ингалируемый состав EA201790832A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462064684P 2014-10-16 2014-10-16
PCT/US2015/055916 WO2016061445A1 (en) 2014-10-16 2015-10-16 Inhalable formulation

Publications (1)

Publication Number Publication Date
EA201790832A1 true EA201790832A1 (ru) 2017-09-29

Family

ID=54361199

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201790832A EA201790832A1 (ru) 2014-10-16 2015-10-16 Ингалируемый состав

Country Status (15)

Country Link
US (1) US10653704B2 (ru)
EP (1) EP3206667A1 (ru)
JP (1) JP6653323B2 (ru)
KR (1) KR20170070151A (ru)
CN (1) CN107106515A (ru)
AR (1) AR102304A1 (ru)
AU (1) AU2015331912A1 (ru)
BR (1) BR112017007589A2 (ru)
CA (1) CA2963143A1 (ru)
CO (1) CO2017004789A2 (ru)
EA (1) EA201790832A1 (ru)
IL (1) IL251664A0 (ru)
MX (1) MX2017004765A (ru)
PE (1) PE20170919A1 (ru)
WO (1) WO2016061445A1 (ru)

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8828477D0 (en) 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
GB9027234D0 (en) 1990-12-15 1991-02-06 Harris Pharma Ltd An inhalation device
ES2079210T3 (es) 1991-12-12 1996-01-01 Glaxo Group Ltd Formulacion farmaceutica de aerosol.
GB9526392D0 (en) 1995-12-22 1996-02-21 Glaxo Group Ltd Medicaments
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
DE10043509A1 (de) * 2000-09-01 2002-03-14 Asta Medica Ag Feste Peptidzubereitungen für die Inhalation und deren Herstellung
SE0004750D0 (sv) * 2000-12-19 2000-12-19 Astrazeneca Ab Novel formulation
AU2003244451A1 (en) * 2002-02-04 2003-09-02 Glaxo Group Limited Amorphous fluticasone 2-furoate, pharmaceutical compositions thereof and its conversion to the crystalline unsolvated form
NZ549589A (en) 2004-02-24 2009-10-30 Microdose Therapeutx Inc Synthetic jet based medicament delivery method and apparatus
WO2007008427A2 (en) * 2005-07-08 2007-01-18 Xemplar Pharmaceuticals, Llc Aerosol compositions and methods
US8196576B2 (en) 2007-02-28 2012-06-12 Microdose Therapeutx, Inc. Inhaler
GB0919465D0 (en) 2009-11-06 2009-12-23 Norton Healthcare Ltd Airflow adaptor for a breath-actuated dry powder inhaler
US9393202B2 (en) 2013-04-26 2016-07-19 Chiesi Farmaceutici S.P.A Particle size reduction of an antimuscarinic compound
CA2963146A1 (en) * 2014-10-16 2016-04-21 Teva Branded Pharmaceutical Products R&D, Inc. Dry powder formulation

Also Published As

Publication number Publication date
WO2016061445A1 (en) 2016-04-21
IL251664A0 (en) 2017-06-29
KR20170070151A (ko) 2017-06-21
EP3206667A1 (en) 2017-08-23
PE20170919A1 (es) 2017-07-12
JP6653323B2 (ja) 2020-02-26
CA2963143A1 (en) 2016-04-21
AU2015331912A1 (en) 2017-05-25
US10653704B2 (en) 2020-05-19
MX2017004765A (es) 2017-07-27
AR102304A1 (es) 2017-02-15
BR112017007589A2 (pt) 2018-01-30
JP2017534611A (ja) 2017-11-24
CO2017004789A2 (es) 2017-09-20
CN107106515A (zh) 2017-08-29
US20170239269A1 (en) 2017-08-24

Similar Documents

Publication Publication Date Title
IL254353B (en) A vaporizing capsule for the vaporization of an active ingredient
FI3674298T3 (fi) Substituoituja indatsoleja, menetelmä niiden valmistamiseksi, niitä sisältäviä farmaseuttisia valmisteita sekä niiden käyttö lääkkeiden valmistukseen
PH12018500544A1 (en) Inhalable nicotine formulations, and methods of making and using thereof
PH12016501841A1 (en) Immunosuppressant formulation
SA517390475B1 (ar) نظام أكياس متعددة وطريقة لتحضير مكونات الدم
EP3560518A4 (en) COMPLEX FOR ADMINISTRATION AND STABILIZATION OF MEDICINAL PRODUCTS AND METHOD FOR MANUFACTURING THEREOF
IN2014CH00840A (ru)
MX2017009289A (es) Formulaciones farmaceuticas que comprenden cangrelor de alta pureza y metodos para preparar y utilizar las mismas.
EA201792512A1 (ru) Составы для доставки антигенов респираторного синтициального вируса и норовируса в тонкий кишечник
SG11201610636VA (en) Pharmaceutical preparation containing entecavir as active ingredient, and preparation method therefor
RS63790B1 (sr) Farmaceutska kompozicija koja sadrži aprepitant i postupak za pripremu iste
EP3708153A4 (en) PREPARATION OF SOLUTION FOR INHALATION BY CARBOCISTEIN AEROSOL, AND PROCESS FOR PREPARATION
EA201790832A1 (ru) Ингалируемый состав
IN2014DE00111A (ru)
GR1008554B (el) Φαρμακευτικο σκευασμα περιεχον εναν αντιμυκητιασικο παραγοντα τριaζολης και μεθοδος για την παρασκευη αυτου
EP3173422A4 (en) Pharmaceutical composition containing, as active ingredient, granulocyte-colony stimulating factor mutant protein or transferrin fusion protein thereof
GB201414271D0 (en) Composition for delivery of an active pharmaceutical substance and method of preparing same
GB201420777D0 (en) Electronic cigarette , Medical drug delivery applicator for the delivery of nicotine extract E-8000
IN2014CH00984A (ru)