EA201590549A1 - Стимуляция развития овариального фолликула и созревания ооцита - Google Patents

Стимуляция развития овариального фолликула и созревания ооцита

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Publication number
EA201590549A1
EA201590549A1 EA201590549A EA201590549A EA201590549A1 EA 201590549 A1 EA201590549 A1 EA 201590549A1 EA 201590549 A EA201590549 A EA 201590549A EA 201590549 A EA201590549 A EA 201590549A EA 201590549 A1 EA201590549 A1 EA 201590549A1
Authority
EA
Eurasian Patent Office
Prior art keywords
stimulation
ovarial
oocyte
follicle
ripening
Prior art date
Application number
EA201590549A
Other languages
English (en)
Inventor
Аарон Дж.У. Швей
Юань Чен
Масаси Дэгути
Кадзухиро Кавамура
Original Assignee
Зе Боард Оф Трастиз Оф Зе Лилэнд Стенфорд Джуниор Юниверсити
Зе Интелектуал Проперти Менеджмент Сентер Ин Зе Ст. Мариана Юниверсити Скул Оф Медисин
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Зе Боард Оф Трастиз Оф Зе Лилэнд Стенфорд Джуниор Юниверсити, Зе Интелектуал Проперти Менеджмент Сентер Ин Зе Ст. Мариана Юниверсити Скул Оф Медисин filed Critical Зе Боард Оф Трастиз Оф Зе Лилэнд Стенфорд Джуниор Юниверсити
Publication of EA201590549A1 publication Critical patent/EA201590549A1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Emergency Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pregnancy & Childbirth (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Finger-Pressure Massage (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Electrotherapy Devices (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Предлагаются способы, которые обеспечивают стимуляцию овариальных фолликулов у млекопитающих посредством нарушения передачи сигнала по пути Hippo.
EA201590549A 2012-09-13 2013-09-13 Стимуляция развития овариального фолликула и созревания ооцита EA201590549A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261700799P 2012-09-13 2012-09-13
US201361778024P 2013-03-12 2013-03-12
PCT/US2013/059800 WO2014043568A1 (en) 2012-09-13 2013-09-13 Stimulation of ovarian follicle development and oocyte maturation

Publications (1)

Publication Number Publication Date
EA201590549A1 true EA201590549A1 (ru) 2015-08-31

Family

ID=50278733

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201590549A EA201590549A1 (ru) 2012-09-13 2013-09-13 Стимуляция развития овариального фолликула и созревания ооцита

Country Status (13)

Country Link
US (1) US20150231209A1 (ru)
EP (1) EP2895185B1 (ru)
JP (1) JP2015531787A (ru)
CN (1) CN105025912B (ru)
AU (1) AU2013315154B2 (ru)
BR (1) BR112015005653A8 (ru)
CA (1) CA2924052A1 (ru)
EA (1) EA201590549A1 (ru)
HK (1) HK1207959A1 (ru)
IL (1) IL237698A0 (ru)
MX (1) MX2015003233A (ru)
NZ (1) NZ706889A (ru)
WO (1) WO2014043568A1 (ru)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104130972B (zh) * 2014-07-09 2017-03-22 南京医科大学 原始卵泡激活剂及其应用
JP2017528459A (ja) * 2014-09-10 2017-09-28 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 卵胞発育及び卵成熟の刺激
CN106177912B (zh) * 2016-07-18 2019-06-18 暨南大学 Ctrp3蛋白的应用
WO2018208628A1 (en) * 2017-05-06 2018-11-15 Memphis Meats, Inc. Compositions and methods for increasing the culture density of a cellular biomass within a cultivation infrastructure
JP7313059B2 (ja) * 2017-05-08 2023-07-24 メハリー メディカル カレッジ 精子細胞を強化するためのヒドロキシ尿素
US11479792B2 (en) 2017-07-13 2022-10-25 Upside Foods, Inc. Compositions and methods for increasing the efficiency of cell cultures used for food production
CA3073543A1 (en) * 2017-08-21 2019-02-28 Vivace Therapeutics, Inc. Benzosulfonyl compounds
EP3793551A4 (en) 2018-05-16 2022-01-26 Vivace Therapeutics, Inc. OXADIAZOLE COMPOUNDS
CN108753699B (zh) * 2018-06-19 2021-04-30 青岛农业大学 一种玉米赤霉烯酮对猪卵母细胞体外发育危害的挽救方法
JP2020050625A (ja) * 2018-09-27 2020-04-02 株式会社北里コーポレーション 卵巣組織の移植方法および卵胞活性化方法
CN113584114A (zh) * 2021-07-07 2021-11-02 中国农业大学 雌性哺乳动物的生殖系统培养体系及其应用
CN114703121A (zh) * 2022-03-29 2022-07-05 广西大学 一种水牛卵巢皮质体外培养用激活培养基及体外培养方法
CN116375861B (zh) * 2023-05-16 2023-08-08 成都大熊猫繁育研究基地 一种抗大熊猫lif单克隆抗体、杂交瘤细胞株及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7850984B2 (en) * 2000-02-15 2010-12-14 The General Hospital Corporation Protection of the female reproductive system from natural and artificial insults
CA2563316A1 (en) 2004-04-06 2005-10-20 Semafore Pharmaceuticals, Inc. Pten inhibitors
US9259438B2 (en) * 2008-01-17 2016-02-16 Kui Liu Methods for in vitro maturation of ovarian follicles
US20100191040A1 (en) * 2009-01-23 2010-07-29 The Board Of Trustees Of The Leland Stanford Junior University Manipulation of ovarian primordial follicles
JP5663841B2 (ja) * 2009-02-23 2015-02-04 富士レビオ株式会社 骨細胞への分化誘導培地及び方法
MX2014007182A (es) * 2011-12-14 2015-04-17 Univ Leland Stanford Junior Estimulacion del desarrollo del foliculo ovarico y maduracion de ovocitos.
WO2013188138A1 (en) * 2012-06-11 2013-12-19 The Regents Of The University Of California Inhibitors of hippo-yap signaling pathway

Also Published As

Publication number Publication date
CN105025912B (zh) 2018-08-21
US20150231209A1 (en) 2015-08-20
CA2924052A1 (en) 2014-03-20
MX2015003233A (es) 2015-11-16
BR112015005653A2 (pt) 2017-08-22
WO2014043568A1 (en) 2014-03-20
EP2895185A4 (en) 2016-07-06
JP2015531787A (ja) 2015-11-05
IL237698A0 (en) 2015-05-31
AU2013315154A1 (en) 2015-04-30
CN105025912A (zh) 2015-11-04
NZ706889A (en) 2016-07-29
EP2895185B1 (en) 2019-07-10
AU2013315154B2 (en) 2018-01-18
HK1207959A1 (en) 2016-02-19
EP2895185A1 (en) 2015-07-22
BR112015005653A8 (pt) 2018-01-30

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