EA201490233A8 - STABLE MEDICAL FORMS OF ARTEROLANA AND PIPERAHIN - Google Patents

STABLE MEDICAL FORMS OF ARTEROLANA AND PIPERAHIN

Info

Publication number
EA201490233A8
EA201490233A8 EA201490233A EA201490233A EA201490233A8 EA 201490233 A8 EA201490233 A8 EA 201490233A8 EA 201490233 A EA201490233 A EA 201490233A EA 201490233 A EA201490233 A EA 201490233A EA 201490233 A8 EA201490233 A8 EA 201490233A8
Authority
EA
Eurasian Patent Office
Prior art keywords
piperahin
arterolana
medical forms
stable medical
stable
Prior art date
Application number
EA201490233A
Other languages
Russian (ru)
Other versions
EA201490233A1 (en
Inventor
Арно Аппавоо Эноуз
Хариш Кумар Мадан
Сумит Мадан
Анупам Трехан
Пунеет Тьяги
Винод Кумар Арора
Саньюкта Бхаттачария
Арьюн Рой
Аннамдевара Балайи
Original Assignee
Ранбакси Лабораториз Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/183,119 external-priority patent/US8664265B2/en
Application filed by Ранбакси Лабораториз Лимитед filed Critical Ранбакси Лабораториз Лимитед
Publication of EA201490233A1 publication Critical patent/EA201490233A1/en
Publication of EA201490233A8 publication Critical patent/EA201490233A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Область изобретения относится к стабильным пероральным лекарственным формам, содержащим спиро- или диспиро-1,2,4-триоксолановые противомалярийные средства или их фармацевтически приемлемые соли, пролекарства и аналоги, а также к способам их получения.The scope of the invention relates to stable oral dosage forms containing spiro- or dispiro-1,2,4-trioxolane antimalarials or their pharmaceutically acceptable salts, prodrugs and analogues, as well as methods for their preparation.

EA201490233A 2011-07-14 2012-07-13 STABLE MEDICAL FORMS OF ARTEROLANA AND PIPERAHIN EA201490233A8 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13/183,119 US8664265B2 (en) 2005-05-18 2011-07-14 Stable dosage forms of spiro and dispiro 1,2,4-trioxolane antimalarials
IN2703DE2011 2011-09-19
IN2156DE2012 2012-07-12
PCT/IB2012/053614 WO2013008218A1 (en) 2011-07-14 2012-07-13 Stable dosage forms of arterolane and piperaquine

Publications (2)

Publication Number Publication Date
EA201490233A1 EA201490233A1 (en) 2014-07-30
EA201490233A8 true EA201490233A8 (en) 2015-01-30

Family

ID=47505579

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201490233A EA201490233A8 (en) 2011-07-14 2012-07-13 STABLE MEDICAL FORMS OF ARTEROLANA AND PIPERAHIN

Country Status (10)

Country Link
EP (1) EP2731603A1 (en)
JP (1) JP2014522856A (en)
KR (1) KR20140053169A (en)
CN (1) CN103930107A (en)
AP (1) AP2014007413A0 (en)
AU (1) AU2012282077A1 (en)
CA (1) CA2850089A1 (en)
EA (1) EA201490233A8 (en)
MX (1) MX2014000463A (en)
WO (1) WO2013008218A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2015008748A0 (en) 2013-02-28 2015-09-30 Sun Pharmaceutical Ind Ltd Stable dispersible formulation of arterolane maleate and piperaquine and process of preparation thereof
KR101698003B1 (en) * 2016-06-20 2017-01-19 여오영 Injectable composition for topical administration for cancer treatment that comprising a quinine salt suspension
CA3083683A1 (en) * 2017-12-12 2019-06-20 Intervet International B.V. Implantable isoxazoline pharmaceutical compositions and uses thereof
CN116322688A (en) * 2020-08-14 2023-06-23 太阳制药工业有限公司 Fixed dose combination for the treatment of malaria

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6486199B1 (en) 2001-06-21 2002-11-26 Medicines For Malaria Venture Mmv International Centre Cointrin Spiro and dispiro 1,2,4-trioxolane antimalarials
US6825230B2 (en) 2002-06-21 2004-11-30 Medicines For Malaria Venture Mmv Spiro and dispiro 1,2,4-trixolane antimalarials
US6906205B2 (en) 2002-06-21 2005-06-14 Medicines For Malaria Venture Mmv Spiro and dispiro 1,2,4-trioxolane antimalarials
EP1898901B1 (en) * 2005-05-18 2016-11-23 Sun Pharmaceutical Industries Limited Stable dosage forms of spiro and dispiro 1,2,4-trioxolane antimalarials
EP2026795A2 (en) * 2006-05-17 2009-02-25 Ranbaxy Laboratories Limited Antimalarial therapy using a combination of synthetic artemisinin derivative and bisquinoline derivative

Also Published As

Publication number Publication date
CN103930107A (en) 2014-07-16
CA2850089A1 (en) 2013-01-17
JP2014522856A (en) 2014-09-08
KR20140053169A (en) 2014-05-07
MX2014000463A (en) 2014-07-09
WO2013008218A1 (en) 2013-01-17
AP3777A (en) 2016-08-31
EA201490233A1 (en) 2014-07-30
EP2731603A1 (en) 2014-05-21
AP2014007413A0 (en) 2014-02-28
AU2012282077A1 (en) 2014-01-30

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