EA200901288A1 - COMPOSITIONS FOR TREATMENT AND METHODS OF TREATMENT OF CHILDREN HYPOGONADISM - Google Patents

COMPOSITIONS FOR TREATMENT AND METHODS OF TREATMENT OF CHILDREN HYPOGONADISM

Info

Publication number
EA200901288A1
EA200901288A1 EA200901288A EA200901288A EA200901288A1 EA 200901288 A1 EA200901288 A1 EA 200901288A1 EA 200901288 A EA200901288 A EA 200901288A EA 200901288 A EA200901288 A EA 200901288A EA 200901288 A1 EA200901288 A1 EA 200901288A1
Authority
EA
Eurasian Patent Office
Prior art keywords
treatment
compositions
methods
hypogonadism
children
Prior art date
Application number
EA200901288A
Other languages
Russian (ru)
Other versions
EA018775B1 (en
Inventor
Роберт И. Дадли
Алан Д. Рогол
Джэнет Бенеш
Трой Л. Замбруннен
Грэг Прэтт
Джон Дж. Бреннан
Хжалмар Лагаст
Original Assignee
Юнимед Фармасьютикалз Ллк
Лаборатуар Безен Энтернасьональ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Юнимед Фармасьютикалз Ллк, Лаборатуар Безен Энтернасьональ filed Critical Юнимед Фармасьютикалз Ллк
Publication of EA200901288A1 publication Critical patent/EA200901288A1/en
Publication of EA018775B1 publication Critical patent/EA018775B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)

Abstract

Настоящее изобретение относится к композициям для лечения препубертатных лиц мужского пола подросткового возраста с недостаточной выработкой тестостерона с помощью водно-спиртовой гелевой композиции с тестостероном, которая обеспечивает, среди прочего, желательный фармакокинетический гормональный профиль, и к способам лечения указанных юношей.The present invention relates to compositions for treating prepubertal male adolescents with insufficient testosterone production using a hydroalcoholic gel composition with testosterone, which provides, inter alia, the desired pharmacokinetic hormonal profile, and methods of treating these young men.

EA200901288A 2007-03-23 2008-03-20 Use of testosterone as hydroalcoholic gel formulation for treating pediatric hypogonadism EA018775B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07104726 2007-03-23
PCT/EP2008/053372 WO2008116825A2 (en) 2007-03-23 2008-03-20 Compositions and method for treating pediatric hypogonadism

Publications (2)

Publication Number Publication Date
EA200901288A1 true EA200901288A1 (en) 2010-04-30
EA018775B1 EA018775B1 (en) 2013-10-30

Family

ID=38321980

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200901288A EA018775B1 (en) 2007-03-23 2008-03-20 Use of testosterone as hydroalcoholic gel formulation for treating pediatric hypogonadism

Country Status (10)

Country Link
EP (1) EP2136813A2 (en)
JP (1) JP2010521519A (en)
CN (1) CN101754764A (en)
AU (1) AU2008231781B2 (en)
BR (1) BRPI0809124A8 (en)
CA (1) CA2623477C (en)
EA (1) EA018775B1 (en)
IL (1) IL200887A0 (en)
MX (1) MX2009008995A (en)
WO (1) WO2008116825A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109481394A (en) * 2011-05-15 2019-03-19 埃瑟尔斯医药有限公司 Intranasal testosterone bioadhesiveness gel preparation and its purposes for treating male hypogonadism

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3755B1 (en) * 2011-01-26 2021-01-31 Ferring Bv Testosterone formulations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6503894B1 (en) * 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US20030139384A1 (en) * 2000-08-30 2003-07-24 Dudley Robert E. Method for treating erectile dysfunction and increasing libido in men
US20040072810A1 (en) * 2001-11-07 2004-04-15 Besins International Belgique Pharmaceutical composition in the form of a gel or a solution based on dihydrotestosterone, process for preparing it and uses thereof
US7138389B2 (en) * 2004-02-09 2006-11-21 University Of Washington Oral androgen therapy using modulators of testosterone bioavailability
CN101287470B (en) * 2005-10-12 2012-10-17 优尼麦德药物股份有限公司 Improved testosterone gel and method of use

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109481394A (en) * 2011-05-15 2019-03-19 埃瑟尔斯医药有限公司 Intranasal testosterone bioadhesiveness gel preparation and its purposes for treating male hypogonadism
CN109481394B (en) * 2011-05-15 2023-05-05 埃瑟尔斯生物医药有限公司 Intranasal testosterone bioadhesive gel formulations and their use for treating male hypogonadism

Also Published As

Publication number Publication date
AU2008231781A1 (en) 2008-10-02
EA018775B1 (en) 2013-10-30
BRPI0809124A8 (en) 2015-11-24
CN101754764A (en) 2010-06-23
CA2623477C (en) 2011-05-31
WO2008116825A3 (en) 2008-11-27
CA2623477A1 (en) 2008-09-23
WO2008116825A2 (en) 2008-10-02
EP2136813A2 (en) 2009-12-30
MX2009008995A (en) 2009-09-03
BRPI0809124A2 (en) 2014-08-26
JP2010521519A (en) 2010-06-24
IL200887A0 (en) 2010-05-17
AU2008231781B2 (en) 2012-09-20

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Legal Events

Date Code Title Description
PC4A Registration of transfer of a eurasian patent by assignment