EA200801823A1 - STRAIN-PRODUCER OF SOLUBLE FORM OF RECOMBINANT HEPSIN PERSON (HPNTM) - Google Patents

STRAIN-PRODUCER OF SOLUBLE FORM OF RECOMBINANT HEPSIN PERSON (HPNTM)

Info

Publication number
EA200801823A1
EA200801823A1 EA200801823A EA200801823A EA200801823A1 EA 200801823 A1 EA200801823 A1 EA 200801823A1 EA 200801823 A EA200801823 A EA 200801823A EA 200801823 A EA200801823 A EA 200801823A EA 200801823 A1 EA200801823 A1 EA 200801823A1
Authority
EA
Eurasian Patent Office
Prior art keywords
soluble form
hpntm
producer
strain
person
Prior art date
Application number
EA200801823A
Other languages
Russian (ru)
Other versions
EA011695B1 (en
Inventor
Евгений Сергеевич СЕВЕРИН
Сергей Евгеньевич СЕВЕРИН
Екатерина Михайловна КУЗНЕЦОВА
Мария Владимировна САВВАТЕЕВА
Михаил Петрович КИРПИЧНИКОВ
Original Assignee
Ано "Институт Молекулярной Диагностики"
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ано "Институт Молекулярной Диагностики" filed Critical Ано "Институт Молекулярной Диагностики"
Priority to EA200801823A priority Critical patent/EA200801823A1/en
Publication of EA011695B1 publication Critical patent/EA011695B1/en
Publication of EA200801823A1 publication Critical patent/EA200801823A1/en
Priority to PCT/RU2009/000300 priority patent/WO2009154514A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Изобретение относится к биотехнологии и может быть использовано для производства хепсина в растворимой форме, который может быть использован в здравоохранении для диагностики рака предстательной железы, а также при лечении онкологических больных, в том числе для получения антител, обладающих способностью связывать в крови хепсин человека.The invention relates to biotechnology and can be used for the production of hepsin in soluble form, which can be used in health care for the diagnosis of prostate cancer, as well as in the treatment of cancer patients, including the production of antibodies that have the ability to bind human hepsin in the blood.

EA200801823A 2008-06-19 2008-06-19 STRAIN-PRODUCER OF SOLUBLE FORM OF RECOMBINANT HEPSIN PERSON (HPNTM) EA200801823A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EA200801823A EA200801823A1 (en) 2008-06-19 2008-06-19 STRAIN-PRODUCER OF SOLUBLE FORM OF RECOMBINANT HEPSIN PERSON (HPNTM)
PCT/RU2009/000300 WO2009154514A2 (en) 2008-06-19 2009-06-15 Producer strain of soluble recombinant human hepsin (hpntm -a)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EA200801823A EA200801823A1 (en) 2008-06-19 2008-06-19 STRAIN-PRODUCER OF SOLUBLE FORM OF RECOMBINANT HEPSIN PERSON (HPNTM)

Publications (2)

Publication Number Publication Date
EA011695B1 EA011695B1 (en) 2009-04-28
EA200801823A1 true EA200801823A1 (en) 2009-04-28

Family

ID=40852079

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200801823A EA200801823A1 (en) 2008-06-19 2008-06-19 STRAIN-PRODUCER OF SOLUBLE FORM OF RECOMBINANT HEPSIN PERSON (HPNTM)

Country Status (2)

Country Link
EA (1) EA200801823A1 (en)
WO (1) WO2009154514A2 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003260316A1 (en) * 2002-07-23 2004-02-09 Bayer Healthcare Ag Regulation of human hepsin
US6977170B2 (en) * 2002-09-06 2005-12-20 Applera Corporation Isolated human hepsin/46 proteins, nucleic acid molecules encoding human hepsin/46 proteins, and uses thereof

Also Published As

Publication number Publication date
EA011695B1 (en) 2009-04-28
WO2009154514A2 (en) 2009-12-23
WO2009154514A3 (en) 2010-02-18

Similar Documents

Publication Publication Date Title
BR112013010857A2 (en) double domain variable imonoglubulines and their uses
EA201291336A1 (en) SUBSTITUTED 5-FLUOR-1H-PYRAZOLOPIRIDINE AND THEIR APPLICATION
PH12016501728A1 (en) Anti-angiogenesis therapy for the treatment of ovarian cancer
IN2012DN02737A (en)
PH12014502507A1 (en) Anti-angiogenesis therapy for the treatment of breast cancer
EA201300558A1 (en) CONNECTIONS AND METHODS FOR MORNING PAIN
UA109633C2 (en) HUMAN ANTIBODY AGAINST TISSUE FACTOR
ME00425B (en) Treatment with anti-vegf antibodies
BR112012008833A2 (en) double variable domain immunoglobulins and uses thereof
EP2987807A3 (en) Antibodies recognising phospho-tau
EA201300016A1 (en) HUMAN ANTIBODY CONJUGATES AGAINST TISSUE FACTOR WITH DRUGS
EA201070553A1 (en) ANTIBODIES TO HEPCIDIN AND VARIANTS OF THEIR APPLICATION
TR201900764T4 (en) Compositions containing LAG-3 and therapeutic antibodies and their use in cancer therapy.
EA201791876A1 (en) MONOCLONAL PROTECTIVE ANTIBODIES AND THEIR APPLICATION
MX2010005244A (en) Compositions and methods for the therapy and diagnosis of influenza.
EA201391119A1 (en) DELIVERY SYSTEMS OF NANOPARTICLES, THEIR RECEIVING AND APPLICATION
TR201907261T4 (en) DKK-1 antibodies.
WO2010135521A3 (en) Compositions and methods for the therapy and diagnosis of influenza
EA201190312A1 (en) SUBSTITUTED PIPERIDINES
EA201591522A1 (en) TREATMENT OF THE TRANSPLANTATE REACTIONS AGAINST THE OWNER OF THE EXPOSED PATIENT TRANSPLANTATION
EA201390530A1 (en) METHOD OF OBTAINING CO-POLYMERA SODIUM CARBOXYMETHYL CELLULOSE AND GOSSIPOL AND ITS APPLICATION IN COMPLEX THERAPY OF PATIENTS WITH AUTHISTIC DISORDERS AND COGNITIVE DISORDERS
MX2012001745A (en) Anti-angiogenesis therapy for the treatment of previously treated breast cancer.
MX2013010367A (en) Compositions and methods for the therapy and diagnosis of influenza.
EA201390867A1 (en) COMPOSITIONS BASED ON CLAY AND LEATHER, METHOD OF THEIR PRODUCTION AND THEIR APPLICATION IN FOOD AND THERAPEUTIC TREATMENT
WO2014100857A8 (en) Vaccines for the treatment of cancer and compositions for enhancing vaccine efficacy

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY KZ RU